Agefeatures of signaling lipids content in rat liver and brain
Loay Khaled Mohammad Hassouneh, Y. Semenova, O. Krasilnikova, N. Babenko
Karazin National University, Kharkiv, Ukraine;Institute of Biology, Kharkiv, Ukraine
Abstract
The effect of age on signaling lipids contents in rat liver and
different brain regions (hippocampus, neocortex) were stud-
ied. The contents of free fatty acids in the brain, diacylglycerol
in liver and ceramide in all tissues studied have been found to
increase with age. Age-dependent accumulation of neutral and
sphingolipids evokes the violation of cell sensitivity to extra-
cellular signals.
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