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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Editorial Board


Editor-in-chief

Vadim SAGACH

Department of Blood Circulation
Bogomoletz Institute of Physiology
Kyiv, Ukraine

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Physiology and pathophysiology of the cardiovascular system

Deputy Chief Editors

ALEXANDR REZNIKOV

Komisarenko Institute for Endochrinology and
Metabolism, Kyiv, Ukraine

Neurohormonal regulation, reproduction and adaptation, experimental andrology

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ELENA LUKYANETZ

Department of Biophysics of Ion Channels
Bogomoletz Institute of Physiology, NASU, Kyiv, Ukraine

Neurophysiology, ion channels, calcium signalling, neuropathology, hypoxia, neurodegeneration, exocytosis

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Editorial Board

OLEH ANDRUKHOV

Associate Professor
University Clinic of Dentistry
Medical University of Vienna, Vienna, Austria

Dental Implants; Inflammation; Periodontal Diseases; Periodontal Ligament; Stem Cell Research; Surface Properties; Titanium; Toll-Like Receptors

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PAVEL BELAN

Department of Molecular biophysics
Bogomoletz Institute of Physiology, NASU, Kyiv, Ukraine

Regulation of intracellular cytoplasmic Ca2+ concentration and Ca2+ signalling in different types of excitable cells as well as modulation of synaptic transmission in norm and pathology.

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TETYANA BEREGOVA

Laboratory of Pharmacology and Experimental Pathology
ESC Institute of Biology, Taras Shevchenko Kyiv National University, Kyiv, Ukraine

Study of mechanisms of neurohumoral regulation of secretory processes in the stomach and transport of water and electrolytes through the epithelium of the colon; establishment of mechanisms of neurohumoral regulation of motor-evacuation function of the gastrointestinal tract; the study of the mechanism of ulcer formation, cytoprotection, the development of precancerous states in the mucous membrane of the stomach and large intestine, the development of methods for their prevention; the study of the role of microflora of different digestive tract biotops in the maintenance of the structural and functional state of the organs of the digestive tract, the development of new methods of surgical treatment and pharmacological correction of diseases of the organs of the digestive system.

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PIOTR BREGESTOVSKI

Aix Marseille Universite, INSERM 1106 Institut de Neurosciences des Systemes,
Marseille, France

Molecular physiology of receptor-operated ion channels

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PAUL BROOKES

Department of Pharmacology,
University of Rochester Medical Center,
Rochester, NY, USA

SIRT1, Acidosis & Metabolism in Cardioprotection, Mitochondrial K+ Channels & Cardioprotection, he role of mitochondrial UPR in ischemic protection

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GENNADII BUTENKO

Department of Cellular and Tissue Technology
Institute of Genetic and Regenerative Medicine of the National Academy of Medical Sciences of Ukraine
Pathophysiology and Immunology Laboratory of the Institute of Gerontology NAMS Ukraine

Age-dependent preconditions for pathology onset in elderly and advanced old age, causes and mechanisms of immune system derangements, as well as developing a number of issues in basic gerontology research. Approaches to immune status correction in elderly people; a role played by the immunological mechanisms in age-associated pathogenesis, stem cells.

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Victor DOSENKO

Department of General and Molecular Pathophysiology
Bogomoletz Institute of Physiology, NASU, Kyiv, Ukraine

Proteasomal proteolysis in ageing, anoxia-reoxygenation, regulation of NO-producing system, etc. investigation of apoptotic and autophagic cell death during anoxia-reoxygenation of the cardiomyocytes and the effect of proteasome inhibitors on these processes. Investigation of the role of allelic gene polymorphism as a risk factor in development of cardio-vascular diseases.

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ALLA FOMINA

Dept. of Physiology and Membrane Biology
University of California
Davis, California USA

Membrane trafficking, t cell exosomes, calcium dynamics, ps receptor localization

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IHOR HUK

Universitat Klinik fur Chirurgie,
Wien Austria

Vascular Surgery, clinical, experimental research (SPACE-Study, L-arginine study)

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Oleg KRISHTAL

Department of Cellular Membranology
Bogomoletz Institute of Physiology, NASU, Kyiv, Ukraine

Cellular Membranology

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EDWARD LAKATTA

Laboratory of Cardiovascular Science,
National Institute on Aging,
National Institutes of Health,
Baltimore, Maryland USA

Identify age-associated changes that occur within the cardiovascular system and to determine the mechanisms for these changes; Myocardial structure and function and determinate how age interacts with chronic disease states to alter function; basic mechanisms in excitation-contraction coupling; the chemical nature and sequence of intermediate reactions controlling the movement of ions through ionic channels and pumps present in myocardium; mechanisms that govern neuro-hormonal behavioral aspects of hypertension; mechanisms of normal and abnormal function of vascular smooth muscle and endothelial cells; potentials and limitations of new therapeutic approaches such as gene transfer techniques.

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MYKOLA MAKARCHUK

Department of Physiology and Anatomy,
ESC Institute of Biology,
Taras Shevchenko Kiev National University, Kyiv, Ukraine

Psychophysiology, the role of the sensorу systems, in particular olfactory analyzer and various types of stress in the behavior of humans and animals, clarification of the participation of the endocannabinoid system of the brain in providing innate and acquired behavioral responses, development of computerized systems for assessing the state of basic psychophysiological functions of a person, studying neurophysiological mechanisms of perception, processing, storage and reproduction of information.

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IRINA MANKOWSKA

Department of Hypoxic States Investigation
Bogomoletz Institute of Physiology, NASU, Kyiv, Ukraine

Specific mechanisms of the hypoxic states development associated with the types of hypoxia, age, gender, and genetic peculiarities covered all links of oxygen transport and utilization in human and animal organisms.

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VASYL’ MOROZ

Pyrogov National Medical University
Vinnitsa, Ukraine

General physiology

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NATALIA PREVARSKAYA

Laboratoire de Physiologie Cellulaire,
Universite de Lille, Lille, France

Ion channels and cancer”. Over these last few years, they have focused their attention on the identification and characterisation of ion channels playing important roles in prostate (and later pancreatic) cancer hallmarks such as 1) self-sufficiency in growth signals and aberrant cell proliferation, 2) insensitivity to antigrowth signals, 3) evasion of programmed cell death (apoptosis), and 4) tissue invasion and metastasis. “Calcium and ion channels signatures” for prostate and pancreatic cancer staging in order to develop reliable prognostic markers and in order to order to develop reliable prognostic markers and define new therapeutic treatment strategies.

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YAROSLAV SHUBA

Department of Neuromuscular Physiology
Bogomoletz Institute of Physiology
Kyiv, Ukraine

Molecular mechanisms of functioning and regulation of ion channels of muscle cells and ascertaining how they are involved in the course of pathological processes, primarily such as cancer, epilepsy and diabetes.

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FRANCESCO VISIOLI

Department of Molecular Medicine,
University of Padova, Italia

Essential fatty acids, namely those of the omega 3, and series natural antioxidants, as related to atherosclerosis and cardiovascular disease. His research ranges from in vitro studies of bioactivity (test tubes, cell cultures) to in vivo tests, performed on laboratory animals and/or humans.

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NANA VOITENKO

Department of Sensory Signalization Physiology
Bogomoletz Institute of Physiology, NASU, Kyiv, Ukraine

Functioning of calcium regulating systems in the neurons of the posterior nasal ganglia and posterior horn of the spinal cord in different models of neuropathic and inflammatory pain. Processing of nociceptive information in the spinal cord.

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ROMAN YANCHIY

Department of Immunophysiology
Bogomoletz Institute of Physiology, NASU, Kyiv, Ukraine

The disclosure of the molecular mechanisms of the pathogenetic action of antibodies on the cardiovascular and reproductive system of the human body.

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PETRO YANCHUK

Department of Physiology and Anatomy,
ESC Institute of Biology,
Taras Shevchenko Kiev National University, Kyiv, Ukraine

Mechanisms of neuro-humoral regulation of activity of the cardiovascular, respiratory and digestive systems.

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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2018.