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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

(English title: Physiological Journal)

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2026; 72(3): 68-72

Metal content in the skin of women with signs of metabolic syndrome

T.M. Falaleyeyva1, N.R. Hrytsevych2, Yu.M. Penchuk1, O.P. Gadilia1, V.V. Vereshchaka1

  1. Taras Shevchenko National University of Kyiv
  2. Andrei Krupynskyi Lviv Medical Academy
DOI: https://doi.org/10.15407/fz72.03.068


Abstract

The role of trace elements in connective tissue metabolism is beyond doubt. In individuals with impaired carbohydrate metabolism, some inorganic substances accumulate in the skin, but the quantitative characteristics remain unstudied. Our study aimed to assess the metal content in the skin of women with signs of metabolic syndrome. The work was based on the results of skin examination of 20 women aged 40 to 55 years who received surgical correction of cosmetic defects and had signs of metabolic syndrome. Determination of the state of free radical oxidation of the skin was carried out directly in skin tissues by the spectrophotometric method. The content of primary (DC) and secondary (MDA) products of lipid peroxidation was determined in skin samples. The protein content in the samples was determined by the Lowry method. An increase in the content of primary and secondary products of lipid peroxidation in the skin was established. Atomic adsorption spectrometry methods have shown an increase in the content of magnesium, cobalt, iron, and calcium and a decrease in the content of nickel and copper in the skin, which contributes to the development of skin fibrosis.

Keywords: skin, metabolic syndrome, lipid peroxidation, 3d-metals

Full text: (PDF, in Ukrainian)

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