Temporomandibular joint disorders are now widely preva- lent in the world, with some studies showing a prevalence of up to 10% among the adult population. The main clinical symptoms include myofascial pain, which primarily reduces the quality of life. The purpose of our work was to determine the effectiveness of the treatment of patients with myofascial pain dysfunction syndrome using the “Dry needling” method in patients with long-term partial secondary adentia. We exam- ined 54 patients, who were divided into two groups: research and control. The patients in the research group underwent the technique of deep puncture of trigger points, and the control group underwent a simulated intervention. Effectiveness was assessed using a visual analog pain scale, the number of trigger points, and the amplitude of bioelectric potentials in the masticatory muscles. According to the visual analog pain scale, the number of points in the research group decreased by 56.61%, and in the control group by 25.71% compared to the pre-treatment index. The number of trigger points in the research group decreased by 62.38%, in the control group decreased by 16.94%. The “Dry needling” treatment method demonstrates effectiveness, which is manifested by a decrease in pain, the number of trigger points, and bioelectrical activity in patients with myofascial pain dysfunction syndrome.