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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2008; 54(6): 42-48


Investigation of the heart functionunder condition of myocardialischemia with the helpof a new methodof electrocardiogram analysis

I.A. CHAIKOVSKY, O.P. NESCHERET,L.S. FAINZILBERG, R. A. ROVENESCH,O.O. MOIBENKO.

    International Research and Training Center for Informa-tional technologies and systems NAS and MES of Ukraine;O.O.Bogomoletz Institute of Physiology, NationalAcademy of Sciences of Ukraine, Kyiv


Abstract

The aim of the paper is to investigate ECG in phase space changes under condition of myocardial ischemia during experi- ments on entire organism. Regional ischemia was simulated in 13 dogs with the help of catheterization of coronary arteries and obturation of one of the left coronary artery branches by plastic embol. All experiments were done with closed chest and natural breathing. Duration of ischemia was 90 min. ECG in phase space was recorded every 10 min. Some parameters of ECG, first of all parameter reflecting symmetry of T wave were evaluated with the help of program-technical complex Fazograph. Rapid and statistically significant increase of parameter ?T un- der influence of myocardial ischemia was observed. Changes of ?T were the earliest and the most sensitive signs of ischemia among all parameters evaluated. Conclusion: Changes of T wave symmetry are sensitive signs of myocardial ischemia, which can be used in clinical practice.

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