According to the positions of systemic analysis of autoregulations and systemic reconstruction processes in children under the in- fluence of PILER-light (Polarized polychromatic incoherent low- energy radiation) depending on the type of general non-specific adaptation reactions of the organism, the clinical blood test has been investigated using the correlation structures method. It has been established that phototherapy with polarized light causes stereotype effect of increased integration between the blood parameters, harmonizing of white and red blood parameters, elimination of the stress, decreased entropy elements. At the same time the specific adaptation reaction of the child’s organism to the loadings of various origin, in particular, to the electromag- netic irradiation of optic diapason waves indicates the diverse character of the changed regulation system functions depend- ing on the adaptation reaction type and grounds the differenti- ated approach to the polarized light therapy.