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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2005; 51(2): 46-50


Heart rate variabiity analysis as ameasure of baroreflex sensitivity

I.A. Khripachenko, A.V. Savustyanenko,L.A. Kedenko, I.I. Zinkovych

    Donetsk Medical University


Abstract

Spectral analysis of the heart rate variability can be used as a measure of baroreflex sensitivity in ketamine anesthetized rats. Stimulation of б1-receptors with phenylephrine (0,01 mg/kg, i.v.) results in a rise of the strength of heart rate regulation, principally in the low frequency band. Maximal deviations of spectral indexes from basal level were observed on 4 – 8 min for low (0,2 – 1 Hz) and high (1 – 3 Hz) frequencies bands and on 10 – 15 min for very low (0,08 – 0,2 Hz) frequency band after phenylephrine injection

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