Heart rate variabiity analysis as ameasure of baroreflex sensitivity
I.A. Khripachenko, A.V. Savustyanenko,L.A. Kedenko, I.I. Zinkovych
Donetsk Medical University
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Abstract
Spectral analysis of the heart rate variability can be used as a
measure of baroreflex sensitivity in ketamine anesthetized
rats. Stimulation of б1-receptors with phenylephrine (0,01
mg/kg, i.v.) results in a rise of the strength of heart rate
regulation, principally in the low frequency band. Maximal
deviations of spectral indexes from basal level were observed
on 4 – 8 min for low (0,2 – 1 Hz) and high (1 – 3 Hz)
frequencies bands and on 10 – 15 min for very low (0,08 – 0,2
Hz) frequency band after phenylephrine injection
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