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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2000; 46(3): 78-83


The Generation of Antihypertensive Peptidesfrom ?-Casein after Modeling Proteolysis

Yukalo V. G., Luhovyy B. L

    Ivan Pului technical University, Ternopil



Abstract

Antihypertensive peptides were obtained after the proteolysis of ?-casein by starter cells Lactococcus lactis ssp. lactis and lactococci with pepsin or fromase. The peptides have shown the effect as inhibitors of angiotensin-converting enzyme. The strongest action the peptide obtained after the proteolysis of ?-casein by synergic action of lactococci with pepsin has shown. It demonstrates a capability of formation of such peptides directly in milk products during their making and maturation under the action of proteolytic system of lactic acid bacteria and milk clothing proteases.

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