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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2000; 46(3): 45-50


Role of Lysosomal Proteinases in the BloodReactions During inflammation

Klimenko N. A., Shevchenko A. N

    Kharlov Medical University


Abstract

On the model of carrageenan — inducced acute aseptic peritonitis in rats it is shown that in inflammation on the bacrground of contrykal administration the accumulation and stimulation of leukocytes of an inflammatory focus, and the activation of granulomonocytopoiesis and of blood leukocytes are increased, and infiltration becomes calm earlier. The results indicate that in the natural М. О. Клименко, О. М. Шевченко 50 ISSN 0201-8489 Фізіол. журн., 2000, Т. 46, № 3 development of inflammation lysosomal proteinases limit the accumulation and stimulation of leukocytes of an inflammatory focus, and activation of granulo- monocytopoiesis and of blood leukocytes, and prolong the inflammatory reaction, i.e. they inhibit the protective adaptive reactions of blood in inflammation.

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