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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2015; 61(1): 78-82


RADIOPROTECTIVE EFFECT OF FOOD IN THE ASSIMILATION OF CARBOHYDRATE SUBSTRATES BY TWO GENERATIONS OF POSTERITY FROM THE RADIATIONEXPOSED MALE RATS

O.V. Storchilo

    Odessa National Medical University
DOI: https://doi.org/10.15407/fz61.01.078


Abstract

The influence of food in the intestine of the radiation-exposed males-predecessors on the functional activity of the small intestine of two generations of their posterity was investigated. It is shown that satiety of these animals during an irradiation determines a radioprotective effect on the systems of transport of carbohydrate substrates of different degree of polymerization only at their posterity of first generation. The second generation had the indexes of functional activity below than that observed in intact group, thus mainly due to a fermentative link. However, here they do not exceed the borders of active component of transport. Consequently, for protection of further generations from the radiation-exposed precursors the more powerful radioprotectors are needed, than simply food.

Keywords: irradiation, small intestine, assimilation of carbohydrates, rats′ posterity.

References

  1. Guryeva VA, Dudareva YuA. The modern estimation of the state of health of descendants of persons being in the zone of radiation-damage (on the example of the Semipalatinsk ground) : Proceeding of the 2nd International scientific-practical conference "Academic science - problems and achievements", Moscow, September 5-6, 2013, P.273 . [Russian].
  2.  
  3. Dergylev aa, Chibisova OF, Palyga GF, Ivanov VL, Zhavoronkov LP. Influence of ionizing radiation in unsteralizing doses on the embryogenesis and post-natal development of posterity of two generations of rats males, the gametes of that were radiation-exposed on the premeyotic stages of spermatogenesis. Rad. and risk, 2012, 21 ( 2) 39-45 [Russian].
  4.  
  5. Liberman A Radiation and reproductive health. SanctPetersburg, 2003 225 p [Russian].
  6.  
  7. Palyga GF, Chibisova OF, Ivanov VL, Dergylev a a, Zhavoronkov LP. Realization of radial effects in the ontogenesis of posterity of two generations of males, whose gametes were radiation-exposed in the nonsterilizide dosage on the stage of mature spermatozoa.  Rad. and risk 2010 19 ( 4) 58-62 [Russian].
  8.  
  9. Palyga GF, Chibisova OF, Ivanov VL, Dergylev a a, Zhavoronkov LP, Panfilova VV, Kolganova OI Realization of radial effects is the ontogenesis of posterity of two generations of males the gametes of which were radiation-exposed singly in unsteralizing doses on the stage of spermatid. Rad. and risk 2011 20 (1) 19-23 [Russian].
  10.  
  11. Reproductive health of new generation: collection of scientific works of Ivanov Scientifically research institute of maternity and childhood the name of V N Gorodkov of Ministry of health and social development of Russian Federation. 2010. Ivanovo: 382 p. [Russian].
  12.  
  13. Agadganyan AV Investigation of the transgenerational phenomenon of genome instability in the the childrendescendants of the radiation-exposed parents as a result of accident on Chernobyl nuclear power station. Moscow 2008 20 p. [Russian].
  14.  
  15. Storchilo OV Peculiarialities of the irradiated rats posterity the small intestine functional activity under the parents life-time different conditions. Odessa Med. Mag. 2009 115( 5) 21-27 [Ukrainian].
  16.  
  17. Ugolev AM, Zhigure DR, Nurks EE,. Accumulating preparation of mucous membrane is a new method of research of the initial stages of transfer of substances through an intestinal wall. Physiol. Mag. of the USSR 1970 56 (11) 1638-1641 [Russian].
  18.  
  19. Scott TA, Melvin EH The determination of hexoses with antrone. Analyt. Chem. 1953 ;25, 1656–58.
  20.  
  21. Storchilo OV Functional activity of the small intestine of two generations of the posterity of the hungry irradiated male rats. Odessa Med. Mag. 2013 140( 6) 13 -17 [Ukrainian].

© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.