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SPECIFIC FEATURES OF CHRONORHYTHMOLOGIC CHANGES OF THE ION-REGULATING FUNCTION OF THE KIDNEYS UNDER THE HYPOFUNCTION OF THE PINEAL GLAND
S.B. Semenenko, S.S. Tkachuk, О.V. Tkachuk, S.Y. Karateeva, V.V. Antsupova
Higher State Educational Establishment of Ukraine “Bukovinian
State Medical University”, Chernivtsi.
DOI: https://doi.org/10.15407/fz62.05.045
Abstract
The paper investigates the specific features of chronorhythmologic
changes of the ion-regulating function of the
kidneys under the hypofunction of the pineal gland. For
the study of hypofunction of the pineal gland, animals were
maintained under constant light stimulation during 7 days. It
has been established that the hypofunction epiphysis point
out disturbances of the phasic structure of the ion-regulating
function in relation to chronograms of the intact group of
rats. In terms of physiological pinealectomy observed increase
in the excretion of sodium ions (6,11±0,81 mmol/h)
and the concentration of this cation in the blood plasma
remained elevated around the clock. The obtained results
indicate significant changes of integral characteristics of the
rhythms of electrolyte metabolism and the important role
of the pineal gland in ensuring physiological homeostasis.
Keywords:
circadian rhythm; kidneys; pineal gland.
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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.
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