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THE LEVEL OF GENERAL IMMUNOGLOBULIN E (IGE) IN RATS OF DIFFERENT AGE WITH ATOPIC DERMATITIS
A.I. Bereznyakova, O.D. Jemela, V.F. Cheremisina
Pharmacological National University of Health of Ukraine, Kharkiv
DOI: https://doi.org/10.15407/fz62.01.092
Abstract
In the article we studied the level of general immunoglobulin
E in rats of different age with atopic dermatitis. On the basis
of the obtained results characteristics are given of levels the
general IgE in rats of different age and it’s increasing with
age. In rats which had been experimentally reproduced atopic
dermatitis the average value of general IgE was increased
in prepubertal rats, mature and old animals significantly
(р<0,001). That can have a diagnostic and predictive value of
this indicator at atopic dermatitis.
Keywords:
allergic dertatitis; rat males of different ages; immunoglobulin E.
References
- Volkoslavskaya VN, Hutnev AL. Condition morbidity of pathology of the skin and infections are sexually transmitted, in the population of Ukraine over the past decade. Clin immunology, allergology, infectology. 2012;1:19–22.
- Cocco R, Sole D. Patch test in the diagnosis of food allergy. Allergol. Immunopathol.2009;37(4):205–7.
CrossRef
PubMed
- Regeda MS, Kresiun VJ, Regeda MM. The state of oxidant and antioxidant systems on bronchus of guinea pigs in conditions development the experimental pneumonia and correction that disorders by corvitin. Odessa Med J.2013;1:21–4. [Ukrainian].
- Novak N. New insights into the mechanism and management of allergic disease: atopic dermatitis.Allergy.2009;64(2):265–75.
CrossRef
PubMed
- Prylutskyi AS, Mailian EA, Kovalenko VV. The levels of immunoglobulin E in the serum blood of healthy persons different age and sick persons with individual disease. J Health Child.2006;2(2):35–7.
- Berezovskiy VA., Bogomolec OV., Derkach NN. About question of endogen regulation of physiological regeneration the human skin. Ukr J Derm Vener Cosmet.2011;42(3):9–14. [Ukrainian].
- Zalkan P, Ievleva E. Effect of synthetic detergents on the reactivity skin of guinea pigs: actual problems of occupation dermatology. Moscow; 1965. [Russian].
- Hmurman VE. Probability theory and medical statistics. Moscow: High School;2001. [Russian].
- Lopach SN, Chubenko AV, Babich PN. Statistic in the science and business. Kyiv: Morion, 2002. [Ukrainian]
- Iancovici Kidon M, Stein M, Geller-Bernstein C. et al. Serum immunoglobulin E levels in Israeli-Ethiopian children: environment and genetics. Issr Med Assoc J.2005;7(12):799–802.
PubMed
- Simoni M, Biavati P, Baldacci S. et al. The Po River Delta epidemiological survey: reference values of total serum IgE levels in a normal population sample of North Italy (8-78 yrs). Eur J Epidemiol.2001;17(3):231–9.
CrossRef
PubMed
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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.
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