Carcinogenic aspects of indeterministic effects of ionizing radiation
Tkachenko MM1, Liubarets' TF2
- O.O. Bogomoletz National Medical University, Ukraine
- Kyiv National Science Center of Radiation Medicine AMS of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz59.06.155
Abstract
The results of clinical and epidemiological investigations on cancer diseases with different localization in irradiated persons are reviewed in the paper. The data on mechanisms of morbidity of mamma, thyroid, broncho-pulmonary, blood cancer in exposed to different doses of ionizing radiation persons are analyzed.
Keywords:
indeterministic effects, ionizing radiation, cancer,leukemia, myelodysplastic syndrome
References
- Bebeshko V.G., Kovalenko A.N., Belii D.A. Ostrii radiatsionnii sindrom i ego posledstviya. Ternopol': TGMU "Ukrmedkniga", 2006. 436 p.
- Belosohov M.V. Patomorfologicheskaya harakteristika raka legkogo u rabotnikov zavoda po proizvodstvu plutoniya: Avtoref. dis. kand. med. nauk. Chelyabinsk, 2006. 45 p.
- Brilliant M.D., Vorob'yov A.I., Gogin E.E. Otdalyonnie posledstviya deistviya malih doz ioniziruyushchei radiatsii na cheloveka . Terap. arhiv. 1987. 59, N 6. P. 3-8.
- Vilenchik M.M. Radiobiologicheskie effekti i okruzhayushchaya sereda. M.: Energoatomizdat, 1983. 136 p.
- Vladimirov V. G. Biologicheskie effekti pri vneshnem vozdeistvii malih doz ioniziruyushchih izluchenii . Voen. med. zhurn. 1989. N 4. P. 44-46.
- Dvadtsyat' p'yat' rokiv Chornobil's'koi katastrofi. Bezpeka maibutn'ogo. Natsional'na dopovid' Ukraini. K.: KIM, 2011. 355 p.
- Dvadtsyat' rokiv Chornobil's'koi katastrofi. Poglyad u maibutnie. Natsional'na dopovid' Ukraini. K.: Atika, 2006. P. 72-74.
- Deet'en P. Nekotorie aspekti biologicheskogo i klinicheskogo deistviya na organizm malih doz ioniziruyushchei radiatsii . Voprosi kurortologii, fizioterapii i lecheb. fiz. kul'turi. 1985. N 5. P. 27-31.
- Zabolevaemost' naseleniya Rossii zlokachestvennimi novoobrazovaniyami v 1995 g. . Pod red. Remennik L.V., Mokinoi V.D., Petrovoi G.V. i dr. M.: MNIOI, 1997. 236 p.
- Il'in B.N. Biologicheskie i meditsinskie aspekti deistviya malih urovnei radiatsii . Radiats. gigiena: Sb. nauch. tr. 1986. P. 27-35.
- Il'in L.A. Kalistratova V.S. Biologicheskoe deistvie inkorporirovannih radionuklidov i osnovi zashchiti organizma . Radiatsionnaya meditsina. Rukovodstvo dlya vrachei-issledovatelei, organizatorov zdravoohraneniya i spetsialistov po radiatsionnoi bezopasnosti . Pod obshch. red. akad. RAMN L.A. Il'ina. T. 1. Teoreticheskie osnovi radiatsionnoi meditsini. M.: Izd-vo AT, 2004. P. 604-653.
- Kashcheev V.V. Radiatsionnie riski onkologicheskoi zabolevaemosti i onkologicheskoi smertnosti sredi uchastnikov likvidatsii posledstvii avarii na Chernobil'skoi AES: Avtoref. dis. ... kand. biol. nauk. Obninsk, 2009. 21 p.
- Kovalenko B.A. Kompleksnii analiz zabolevaemosti zlokachestvennimi novoobrazovaniyami naseleniya Belgorodskoi oblasti v postchernobil'skoi period: Avtoref. dis. ... kand. med. nauk. Obninsk, 2005. 39 p.
- Koggl Dzh. Biologicheskie effekti radiatsii. M.: Energoatomizdat, 1986 . 184 p.
- Koshurnikova, N. A. Otdalennie posledstviya vdihaniya plutoniya-239 u cheloveka i zhivotnih: Avtoref. dis. d-ra. med. nauk. M., 1978. 435 p.
- Koshurnikova N.A, Komleva N.I., Baisogolov G.I. Effekt oblucheniya u personala PO "Mayak". M.: NIMB YaO SSSR, 1992. N 4. P. 18-21.
- Kudryashov Yu.B. Radiatsionnaya biofizika (ioniziruyushchie izlucheniya). M.: Fizmatlit, 2004. 448 p.
- Kuzin A.M. Stimuliruyushchee deistvie ioniziruyushchego izlucheniya na biologicheskie protsessi (k probleme biologicheskogo deistviya malih doz). M.: Atomizdat, 1977. 135 p.
- Kuznetsova I.S. Zabolevaemost' i smertnost' ot leikoza sredi personala PO «Mayak» i ostal'nogo naseleniya goroda Ozerska: Avtoref. dis. ... kand. biol. nauk. M., 2004. 37 p.
- Lihtarev i.A., Kairo I.A., Shpak V.M., M., Tron'ko N.D., Bogdanova T.N. Radioindutsirovannii i spontannii rak shchitovidnoi zhelezi u detei Ukraini (dozimetricheskaya interpretatsiya) . Mezhdunarod. zhurn. radiats. meditsini. 1999. N 3-4. P. 51-66.
- Lyubarets T.F. Sovremennie predstavleniya o vozdeistvii ioniziruyushchego izlucheniya na organizm cheloveka . Likar. sprava. 1995. N 3-4. P. 15-22.
- Mal'tsev V.N., Evseeva N.K. Estestvennii immunitet i autosensibilizatsiya votdalennie sroki posle vozdeistviya ioniziruyushchei radiatsii . Otdalennie posledstviya luchevih porazhenii. M.: Atomizdat, 1971. P. 113-119.
- Minchenko Zh.M. Imunogenetichni chinniki v mehanizmah radiochutlivosti organizmu lyudini i riziku realizatsii postradiatsiinih efektiv na rivni disfunktsii v imunopoezi ta formuvanni somatichnoi patologii v osib, oprominenih vnaslidok avarii na ChAES . Medichni naslidki avarii na Chornobil's'kii atomnii elektrostantsii . Za red. Vozianova O.F., Bebeshka V.G., Baziki D.A. K.: DIA, 2007 . P. 413-421.
- Parshkov E.M., Sokolov V.A., Proshin A.D., Stepanenko V.F. Rak shchitovidnoi zhelezi u detei i vzroslogo naseleniya Bryanskoi oblasti posle avarii na Chernobil'skoi AES . Vopr. onkologii. 2004. 50, N 5. P. 533-539.
PubMed
- Pilipenko M.I. Stohastichni efekti oprominennya . Ukr. radiol. zhurn. 2012. 20, vip.1. P. 44-50.
- Prisyazhnyuk A.Ie., Romanenko A.Yu., Grishchenko V.G., Fedorenko Z.P., Gulak L.O., Goroh Ie.L., Gudzenko N.A., Trotsyuk N.K., Slipenyuk K.M., Polishchuk Zh.M. Uzagal'nennya 20-richnogo dosvidu doslidzhennya mozhlivih onkologichnih naslidkiv Chornobil's'koi katastrofi v Ukraini .Medichni naslidki avarii na Chornobil's'kii atomnii elektrostantsii . Za red. Vozianova O.F., Bebeshka V.G., Baziki D.A. K.: DIA, 2007. P. 91-106.
- Ramzaev P. V., Miretskii G. I., Troitskaya M. N. Gigienicheskaya otsenka radiatsionnoi obstanovki v raionah, prilegayushchih k Novozemel'skomu ispitatel'nomu poligonu: Otchet o NIR Leningradskogo NII radiatsionnoi gigieni, 1991. 70 p.
- Sokolov V.A. Biologicheskie i radiatsionno-himicheskie effekti neitronnogo oblucheniya kletok Escherichia coli i makromolekul: Avtoref. dis. … kand. biol. nauk. Obninsk, 1984. 188 p.
- Tkachenko M.M., Lyubarets' T.F. Genetichni aspekti indeterministichnih efektiv ionizuyuchogo viprominyuvannya . Fiziol. zhurn. 2012. 58, N 5. P. 76-83.
- Filippova L.G., Nifatov A.P. Opuholevie effekti u kris posle vozdeistviya malih doz gamma-izlucheniya . Vsesoyuz. konf. po deistviyu malih doz ioniz. radiatsii, Sevastopol', oktyabr', 1984: tezisi dokl. K.: Nauk. dumka, 1984. P. 97-98.
- Tsib A.F., Budagov R.S., Zamulaeva I.A. Radiatsiya i patologiya . Pod obshch. red. A.F. Tsiba. M.: Vissh. shkola, 2005. 341 p.
- Beir V. Committee on the Biological Effects of Ionizing Radiations. Health Effects of Exposure to Low Levels of Ionizing Radiation National Academy of Sciences, National Research Council . Washington: Nat. Acad. press, 1990. 421 p.
- Boice J.D. Thyroid disease 60 years after Hiroshima and 20 years after Shernobyl . JAMA. 2006. 295. P. 1060-1062.
CrossRef
PubMed
- Bond V.P. The Cancer Risk Attributable to Radiation Exposure: Some Practical Problems . Health Physics. 1981. 40. P. 111-113.
- Brenner D.J., Hall E.J. Computed tomography is incrising source of radiation exposure . N. Engl. J. Med. 2007. 357. P. 2277-2284.
CrossRef
PubMed
- Brindel P., Doyon F., Bourgain C., Rachédi F., Boissin J.L., Sebbag J., Shan L., Bost-Bezeaud F., Petitdidier P., Paoaafaite J., Teuri J., de Vathaire F. Family history of thyroid cancer and the risk of differentiated thyroid cancer in French Polynesia . Thyroid. 2010. 20, N 4. P. 393-400.
CrossRef
PubMed
- Cardis E., Vrijheid M., Blettner M. Gilbert E., Hakama M., Hill C., Howe G., Kaldor J., Muirhead C. R., Schubauer-Berigan M., Yoshimura T., Bermann F., Cowper G., Fix J., Hacker C., Heinmiller B., Marshall M., Thierry-Chef I., Utterback D., Ahn Y-O., Amoros E., Ashmore P., Auvinen A., Bae J-M., Bernar J., Biau A., Combalot E., Deboodt P., Diez Sacristan A., Eklöf M., Engels H., Engholm G., Gulis G., Habib R.R., Holan K., Hyvonen H., Kerekes A., Kurtinaitis J., Malker H., Martuzzi M., Mastauskas A., Monnet A., Moser M., Pearce M. S., Richardson D. B., RodriguezArtalejo F., Rogel A., Tardy H., Telle-Lamberton M., Turai I., Usel M., Veress K. The 15-country collaborative study of cancer risk among radiation workers in the nuclear industry: estimates of radiation-related cancer risks . Rad. Res. 2007. 167, N 4. P. 396-416.
CrossRef
PubMed
- Cardis E., Gilbert E.S., Carpenter L. Howe G., Kato I., Armstrong B.K., Beral V., Cowper G., Douglas A., Fix J., Fry S.A., Kaldor, Lave C., Salmon L., Smith P.G., Voelz G.L., Wiggs L.D. Effects of low doses and low dose rates of external ionizing radiation: cancer mortality among nuclear industry workers in three countries . Ibid. 1995. 142. P. 117-132.
- Darby S.C., Doll R., Gill S.K., Smith P.G. Long term mortality after a single teratment course with X-rays in patients treated for ankylosing spondylities . Brit. J. Cancer. 1987. 55. P. 179-190.
CrossRef
PubMed PubMedCentral
- Field R.W. Environmental Factors in Cancer: Radon, Reviews on Environmental Health Special Edition (Part 2). 2010. 25 (1). P. 25-31.
- Finch S.C. Radiation-induced leukemia: lessons from history . Best Pract. Res. Clin. Haematol. 2007. 20. P. 109-118.
CrossRef
PubMed
- Frazer P., Carpenter L., Maconochie N. Cancer mortality and morbidity in employees of the United Kindom Atomic Energy Authority, 1946-1986 . Brit. J. Cancer. 1993. 67, N 3. P. 615-624.
CrossRef
- Hatch M., Ron E., Bouville A., Zablotska L., Howe G. The Chernobyl disaster: cancer following the accident at the Chernobyl . Nucl. Power Plant. Epid. Rev. 2005. 27. P. 56-66.
- Hsu W.-L., Preston D.L., Soda M., Sugiyama Y., Funamoto S., Kodama K., Kimura A., Kamada N., Dohy H., Tomonaga M., Iwanaga M., Miyazaki Y., Cullings H.M., Suyama A., Ozasa K., Shorea R.E., Mabuchii K. The Incidence of Leukemia, Lymphoma and Multiple Myeloma among Atomic Bomb Survivors: 1950-2001 . Radiat. Res. 2013. 179. P. 361-382.
CrossRef
PubMed PubMedCentral
- IARC Monographs on the Evaluation of Carcinogenic Risk to Humans. Ionizing Radiation, Part 1: X- and Gamma (γ)-Radiation, and Neutrons- Lyon: IARC press, 2000. Vol. 75. 491 p.
- IARC Monographs on the Evaluation of Carcinogenic Risk to Humans. Ionizing Radiation, Part 2: Some Internally Deposited Radionuclides. Lyon: IARC press. 2001. Vol. 78. 595 p.
- Ivanov V.K., Tsyb A.F., Gorsky A.I., Maksyutov M.A., Rastopchin E.M., Konogorov A.P., Korelo A.M., Biryukov A.P., Matiash V.A. Leukemia and thyroid cancer in emergency workers of the Chernobyl accident: estimation of radiation risks . Rad. Invir. Biophys. 1997. 36. P. 9-16.
CrossRef
- Kerber R.A. A cohort study of thyroid disease in relation to fallout from nuclear weapons testing . JAMA. 1993. 270, N 17. P. 2076-2082.
CrossRef
PubMed
- Linet M.S., Murbeth S., Rousarova M., Scherb H., Lengfelder E. Thyroid cancer has increased in the adult population of countries moderately affected by Chernobyl fallout . Med. Sci. Monit. 2004. 108, N 7. P. 300-306.
- Morgan W.F. Non-target and delayed effects of exposure to ionizing radiation: I. Radiation induced genomic instability and bystander effect in vitro . Radiat. Res. 2009. 165. P. 567-580.
- Murbeth S., Rousarova M., Scherb H., Lengfelder E. Thyroid cancer has increased in the adult population of countries moderately affected by Chernobyl fallout . Med. Sci. Monit. 2004. 108, N 7. P. 300-306.
- Pierce D., Shimizu Y., Preston D., Vaeth M., Mabuchi K. Studies of the mortality of atomic bomb survivors. Report12. Part I. Cancer: 1950-1990 . Radiat. Res. 1996. 146. P. 1-27.
CrossRef
PubMed
- Preston D.L., Kusumi S., Tomonaga M., Izumi S., Ron E., Kurato N., Dohy N., Matsui T., Nonaka H., Thompson D.H., Soda M., Mabuchi K. Cancer incidence in atomic bomb survivors. Part III. Leukemia, lymphoma and multiple myeloma, 1950-1987 . Ibid. 1994. 137. P. 68-97
CrossRef
- RADECS-2005 (The 8th European Conference on Radiation and its Effects on Components and Systems Overview, Cap d'Agde, Sept. 19-23, 2005 . IEEE Trans. Nucl. Sci. 2005. 53, N 4, Pt. 1. P. 1412-1429.
- Rericha V., Kulich M., Rericha R. Shore D.L., Sandleret D.P. Incidence of leukemia, lymphoma and multiple myeloma in Czech uranium miners: a case-control study . Envir. Health Res. 2006. 114, N 6. P. 818-822.
- Romanenko A., Bebeshko V., Hatch M., Bazyka D., Finch S., Dyagil I., Reiss R., Chumak V. The UkrainianAmerican study of leukemia and related disoders among Chornobyl cleanup workers: I. Study methods . Radiat. Res. 2008. 170, N 6. P. 691-697.
CrossRef
PubMed PubMedCentral
- Shimizu Y., Kato H., Schull W.J. Studies of the mortality of Atomic bomb survivors. Mortality: 1950-1985: Part 2. Cancer mortality based on the recently revised doses (DS86) . Ibid. 1990. 21. P. 120-141.
- Tefferi A., Thiele J., A. Orazi A., Kvasnicka H. M., Barbui T., Hanson C.A., Barosi G., Verstovsek S., Birgegard G., Mesa R., Reilly J.T., Gisslingeret H. Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recoommendations from an international expert pannel . Blood. 2007. 110, N 4. P. 1092-1097.
CrossRef
PubMed
- Tokarskaya Z.B., Okladnikova N.D., Belyaeva Z.D., Drozhko E.G. Multifactorial analysis of lung cancer doseresponse relationships for workers at the Mayak nuclear enterprise . Health Phys. 1997. 73, N 6. P. 899-905.
CrossRef
PubMed
- Zablotska L.B., Bazyka D.A., Lubin J.H., Gudzenko N., Little M.P., Hatch M., Finch S., Dyagil I., Reiss R.F., Chumak V.V., Bouville A., Drozdovitch V., Kryuchkov V.P., Golovanov I., Bakhanova E., Babkina N., Lubarets T., Bebeshko V., Romanenko A., Mabuchi K. Radiation and the Risk of Chronic Lymphocytic and Other Leukemias among Chornobyl Cleanup Workers . Environmental Health Perspectives. 2013. 121, N 4. P. 59-65.
CrossRef
PubMed PubMedCentral
|