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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2013; 59(6): 30-36


Functional and morphological changes of the diencephalon vascular endothelium of rats in experimental ischemia-reperfusion injury and diabetes mellitus

Boĭchuk TM, Savchuk TP

    Bucovina State Medical University, Chernivtsi, Ukraine
DOI: https://doi.org/10.15407/fz59.06.030

Abstract

We have studied the influence of bilateral carotid ischemia-reperfusion on the indices of the functional and morphological condition of the vascular endothelium of the brain hypothalamolimbic complex. It has been established that a decrease of the density of endothelial location in an early ischemic-reperfusion period in the control rats has a relative characterstipulated by edema of cells whereas on the 12-th day of observation an increase of the absolute density of cells takes place. During both periods of observation there is an increased content of the tjtal RNA in the capillary endotheliocytes of all the structures. An early reaction of the morpho-functional states of endotheliocytes to ischemic-reperfusion is absent in animal with diabetes mellitus, exept the vessels of the ventromedial hypothalamus while a late one is restricted by a growth content in RNA cells.

Keywords: hypothalamus, intermittent hypoxia, neuropeptides

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