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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2001; 47(2): 41-45


Influence of ferrum and zincum elementson lead absorption by a tunica mucosaof different departments of small bowel

S.P. Lugovskoy

    Ukrainian Scientific Research Institute of Industrial MedicineMinistry of Public Health, Krivoy Pog


Abstract

During experiments on turned out sacs models of duodenum, jejunum and ileum of rats the differences in levels of exogenous Pb2+ absorption were revealed. The most values were in tunica mucosa (TM) of duodenum and jejunum. Pb2+ absorption was influenced by previous exposure to trace elements (TE) of Fe2+ (0,79 mmole/100g) and Zn2+ (0,36 mmole/100g) having been inducted to stomach. TE due to their physical and chemical properties reduced Pb2+ absorption in different parts of intestine TM on the average by 14—49%. It was determined that TE prevented Pb2+ absorption in TM of intestine more effectively during combined introduction compared to isolated Вплив мікроелементів заліза 2 № ,74 .Т ,1002 ,.нруж .лоізіФ 9848-1020 NSSI45 one (accordingly 42% in duodenum, 43% in ileum and 29% in jejunum). Reducing Pb+ absorption is explained by probable substrates competition for active centers of their binding and transfer to TM of intestine.

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