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Influence of ferrum and zincum elementson lead absorption by a tunica mucosaof different departments of small bowel
S.P. Lugovskoy
Ukrainian Scientific Research Institute of Industrial MedicineMinistry of Public Health, Krivoy Pog
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Abstract
During experiments on turned out sacs models of duodenum, jejunum and ileum of
rats the differences in levels of exogenous Pb2+ absorption were revealed. The most
values were in tunica mucosa (TM) of duodenum and jejunum. Pb2+ absorption was
influenced by previous exposure to trace elements (TE) of Fe2+ (0,79 mmole/100g)
and Zn2+ (0,36 mmole/100g) having been inducted to stomach. TE due to their
physical and chemical properties reduced Pb2+ absorption in different parts of intestine
TM on the average by 14—49%. It was determined that TE prevented Pb2+ absorption
in TM of intestine more effectively during combined introduction compared to isolated
Вплив мікроелементів заліза
2 № ,74 .Т ,1002 ,.нруж .лоізіФ 9848-1020 NSSI45
one (accordingly 42% in duodenum, 43% in ileum and 29% in jejunum). Reducing
Pb+ absorption is explained by probable substrates competition for active centers of
their binding and transfer to TM of intestine.
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