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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2013; 59(2): 96-99

Changes parameters of humoral immunity in abdominal tuberculosis

Lapovets' NIe

    Danylo Halytskyy National Medical University, Lviv, Ukraine
DOI: https://doi.org/10.15407/fz59.02.096


Abstract

We measured the levels of IL-1beta, IL-8, and TNF-alpha, as well as humoral immunity in blood serum of patients with abdominal tuberculosis before and after Koch's test. The content of TNF-alpha increased 2.5 times, the content of IL-8 decreased almost twice, and concentration of IL-1beta decreased three times compared to the controls. We found that Koch's test exacerbates pathogenic manifestations of chronic inflammation which shows changes in cytokine spectrum of blood and allows us to refine diagnosis of abdominal tuberculosis.

Keywords: cytokines, humoral immunity, abdominal tuberculosis.

Full text: (PDF, in Ukrainian)

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