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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2001; 47(1): 80-84


Study of antioxidative homeostasis of sick peoplein critical state

E. M. Klimova, A. V. Paranich, I. Yu. Voloshina, N. V. Efimova,Yu. A. Suprun

    Kharkov State University Ministry of Education of Ukraine


Abstract

IN CRITICAL STATE Content of primary and secondary products of lipid peroxidation, fat soluble vitamins: A, E, carotene, tocopherol.s metabolites and total antioxidative activity were investigated in experiments with serum blood of donors and sick people with the .en. 2. Oaiie iaeiie.ai- iy .e.i.ic.eiieo aioa- iiiia, iaoaaieioia oieioa- .ieo oa caaaeuii. aioe- ieeni.aaeuii. aeoeaiinoi (AIA) e.iai o oai.eo c aino.i. oi.o.ai.ii. o.aa- ii. (o aianioeao aia- iinii iiia.aaiuiai ae- ii.o): I . aeia.e oiei- oa.ieo; II . oieioa.ee- oiiii; III . aioaiii .; IV . aioaiii A; V . ea.ioei; VI . caaaeuia AIA; 1 . 1-oa aiaa, 2 . 3-oy aiaa, 3.7-ia aiaa. I. I. Eeeiiaa oa .i. 84 ISSN 0201-8489 O.c.ie. .o.i., 2001, O. 47, . 1 acute surgical trauma. It was showed that during the critical states of sick people there is watched the strain of adaptive systems of the whole organism with the resource mobilisation of fat soluble vitamins and appearance of signs of their exhaustion, modification of the direction of metabolism of the unsaturated fat acids from certain formation of eicosanoids to the avalanche looking lipid peroxidation with the accumulation of poisonous products in blood. Also there intensify the formation of active tocopherol.s metabolites, what is necessary for the re-establishment of the violative balance in the system of antioxidative protection. Kharkov State University Ministry of Education of Ukraine

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