Peculiarities of bile formation in rats of different sex under estron influence
Klymiuk OV, Bondzyk OV, Reshetnik IeM, Vesel's'kyĭ SP, Makarchuk MIu
Taras Shevchenko Kyiv National University, Ukraine
DOI: https://doi.org/10.15407/fz57.06.052
Abstract
The influence of estron (8 ug/100g of animal’s body weight) on the exocrine function of liver and the changes in bile acid composition of bile on different sex rats was studied. It was shown, that hormone at the applied dose, effected choleresis of female rats more effectively. Estron also caused different changes in bile composition. So, estron stimulated bile acid conjugation with taurine and glycin in female rat liver. Increasing of free and conjugated bile acid biosynthesis in male rats was observed.
Keywords:
estron, choleresis, bile, bile acids.
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