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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2011; 57(3): 10-15

Insulin resistance and physical performance in middle age and elderly people

Korkushko OV, Ishchuk VO, Shatylo VB, Chyzhova VP

    Institute of Gerontology AMS of Ukraine, Kyiv, Ukraine


In 43 middle age and elderly people without obesity (body mass index of less than 30 kg/m2) we studied the relationship between insulin resistance (IR) and physical performance. It is shown that in healthy elderly IR is associated with a moder­ate increase of insulin and a small increase in the level of glu­cose in the blood plasma. In the middle age people, IR has no effect on physical performance. IR in the elderly people is accompanied by the decrease in physical performance due to less economical for hemodynamic load and oxygen consump­tion. A lower exercise tolerance in elderly people without obe­sity can be considered not only as a risk factor for insulin resistance, but also as its consequence.

Keywords: physical performance, insulin resistance, middleage, elderly


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