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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2011; 57(2): 76-89


Physiological adaptations to weightlessness: the contractile propertiesand fatiguability of the human triceps surae muscle after exposure to simulated microgravityenvironments

Yuri Koryak

    Учреждение РАН «Гос. Науч.-центр


Abstract

This study examined the effects of short- (1-, and 3-day) and long-term (7-day) .dry. immersion (DI) on neuromuscular function of human the triceps surae muscle. The isometric twitch tension (Pt) decreased by 8.7% after 1-days, but increased by 11.5 and 9.8 % after 3- and 7-days DI, respectively. Maximal voluntary contraction (MVC) decreased by 13.6, 19.7, and 33.8 % after 1-, 3-, and 7-days DI, respectively (p < 0.05 - 0.01), electrically evoked (frequency of 150 impulses/s) tetanic tension (Po) reduced by 1.8, 5.3, and 8.2 %, respectively, (nonsignificant). The difference between Po and MVC expressed as a percentage of Po and referred to as force deficiency (Fd) was also calculated. Fd increased by 23.4, 20.2, and 78.7 % after 1-, 3-, and 7-days, respectively (p < 0.05-0.001). After DI, the time-to-peak tension (TPT), half-relaxation time (1/ 2 RT), and total contraction time (TCT) was reduced. The TPT decreased by a mean value of 8.5, and 3.3 % after 1- and 3-days, respectively, and after 7-day did not reveal significant changes in the curve of the TPT. 1/2 RT and TCT was shorter in the post-immersion condition than in the control value. The rate of increase of voluntary contraction calculated according to relative scale was significantly reduced after DI (p < 0.05- 0.001), but for the electrically evoked contraction (frequency of 150 impulses.s-1) there were no substantial changes from the initial physiological state. A standard 2-min fatigue of electrically-induced intermittent test (frequency of 50 impulses.s-1) did not differ substantially from the initial physiological state, but the electrical M-waves reduced significantly. The relative extent of the decline in either of these two parameters can be determined from the change in the relation of the electrical Mwave to the contractile response (the E/C ratio). After longterm DI (7 day) of muscle a significantly greater decline of electrical waves is observed as compared to contractile response by a short-term DI (1-, and 3-day), respectively.

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