Українська English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2011; 57(2): 76-89


Functional characteristics of human neuro-muscular system and their changes as a result of mechanical unloading of different duration

Koriak IuA

    State Scientific Center - Institute of Biomedical Problems, Department of Neurophysiology and countermeasures, Moscow, Russia
DOI: https://doi.org/10.15407/fz57.02.076


Abstract

This study examined the effects of short- (1-, and 3-day) and long-term (7-day) .dry. immersion (DI) on neuromuscular function of human the triceps surae muscle. The isometric twitch tension (Pt) decreased by 8.7% after 1-days, but increased by 11.5 and 9.8 % after 3- and 7-days DI, respectively. Maximal voluntary contraction (MVC) decreased by 13.6, 19.7, and 33.8 % after 1-, 3-, and 7-days DI, respectively (p < 0.05 - 0.01), electrically evoked (frequency of 150 impulses/s) tetanic tension (Po) reduced by 1.8, 5.3, and 8.2 %, respectively, (nonsignificant). The difference between Po and MVC expressed as a percentage of Po and referred to as force deficiency (Fd) was also calculated. Fd increased by 23.4, 20.2, and 78.7 % after 1-, 3-, and 7-days, respectively (p < 0.05-0.001). After DI, the time-to-peak tension (TPT), half-relaxation time (1/ 2 RT), and total contraction time (TCT) was reduced. The TPT decreased by a mean value of 8.5, and 3.3 % after 1- and 3-days, respectively, and after 7-day did not reveal significant changes in the curve of the TPT. 1/2 RT and TCT was shorter in the post-immersion condition than in the control value. The rate of increase of voluntary contraction calculated according to relative scale was significantly reduced after DI (p < 0.05- 0.001), but for the electrically evoked contraction (frequency of 150 impulses.s-1) there were no substantial changes from the initial physiological state. A standard 2-min fatigue of electrically-induced intermittent test (frequency of 50 impulses.s-1) did not differ substantially from the initial physiological state, but the electrical M-waves reduced significantly. The relative extent of the decline in either of these two parameters can be determined from the change in the relation of the electrical Mwave to the contractile response (the E/C ratio). After longterm DI (7 day) of muscle a significantly greater decline of electrical waves is observed as compared to contractile response by a short-term DI (1-, and 3-day), respectively.

References

  1. Badalyan LO, Skvortsov IA Clinical electromyography. M .: Medicine, 1986. 386 p.
  2.  
  3. Koryak Yu.A. Methods for the study of the neuromuscular system in athletes. M .: IMBP, 1992. 63 p.
  4.  
  5. Koryak Yu.A. Comparison of contractile properties of the muscles of the lower extremities in humans . Fiziol Zh. 1994. 40. p. 30-38.
  6.  
  7. Koryak Yu.A., Polyakov VV, Potsepayev AI, Martyanov VA Investigation of the dynamic performance of the peripheral neuromuscular apparatus of athletes. In book: Physiological bases of motion control. M .: VNIIFK, 1975. P. 73-74.
  8.  
  9. Kotz YM, Kuznetsov SP. The method of evaluation of "anaerobic" performance of the peripheral neuromuscular apparatus in athletes . Theory and Practice of Phys. culture. 1971. N 10. P. 24-29.
  10.  
  11. Skvortsov IA Electroneuromyography. Method. Dynamics of indications in ontogeny. In book: Clinico-electromuscular study of neuromuscular diseases and syndromes. 1981. P. 37-71.
  12.  
  13. Shulzhenko EV, Wil-Williams IF Possibility of long water immersion by the method of "dry" immersion . Kosm. biology and aerospace. medicine. 1976 10. P. 82-84.
  14.  
  15. Always S.E., Sale D.G., MacDougall J.D. Twitch contractile adaptations are not dependent on the in­tensity of isometric exercise in the human triceps surae . Eur. J. Appl. Physiol. 1990. 60. P. 346-352. CrossRef PubMed
  16.  
  17. Bachl N., Tschan H., Baron R., Kozlovskaya I.B., Koryak Yu., Mossaheb M., Albrecht R. Muscular de-conditioning during long-term spaceflight exercise recommendations to optimize crew performance . 12th Man in Space Simposium: The future of humans in space simposium. Washington. DC, 1997. P. 303.
  18.  
  19. Bezanlilla F., Caputo C, Gonzalez-Serratos H., Venosa R.S. Sodium dependence of the inward spread of activation in isolated twitch muscle fibers of the frog . J. Physiol. 1972. 223. P. 507-523. CrossRef PubMed PubMedCentral
  20.  
  21. Bigland-Ritchie B.R., Johansson R., Lippold O.C.J., Smith S., Woods J.J. Changes in motoneuron firing rates during sustained maximal voluntary contractions . Ibid. 1983. 340. P. 335-346. CrossRef PubMed PubMedCentral
  22.  
  23. Bigland-Ritchie B.R., Jones D.A., Woods J.J. Excita­tion frequency and muscle fatigue: electrical responses during human voluntary and stimulated contraction . Exp. Neurol. 1979. 64. P. 414-427. CrossRef  
  24. BriggsF.N., Poland J.L., Solard R.J. Relative capabilities of sarcoplasmic reticulim in fast and slow mammalian skeletal muscle . J. Physiol. 1977. 266. P. 587-594. CrossRef PubMed PubMedCentral
  25.  
  26. Buller A.J., Lewis D.M. The rate of tension develop­ment in isometric tetanic contractions of mammalian fast and slow skeletal muscle . Ibid. 1965. 176. P. 337-354. CrossRef PubMed PubMedCentral
  27.  
  28. Close R. Dynamic properties of mammalian skeletal muscle . Physiol. Rev. 1972. 52. P. 129-197. CrossRef PubMed
  29.  
  30. Duchateau J, Hainaut K. Effects of immobilization on contractile properties recruitment and firing rates of human motor units . J. Physiol. 990. 422. P. 55-65. CrossRef PubMed PubMedCentral
  31.  
  32. EdgertonV.R., ZhouM.Y., OhiraY., Klitgaard H., Jjang Bell B., Harris B., Saltin B., Gollnick P.D., Roy R.R., Day K., Greenisen M. Human fiber size and enzymatic properties after 5 and 11 days of space­flight . J. Appl. Physiol. 1995. 78. P. 1733-1739. CrossRef PubMed
  33.  
  34. Garnett R., Stephens J.A. Changes in the recruitment threshold of motor units produced by vutaneous stimulation in man . J. Physiol. 1981. 311. P. 463-473. CrossRef PubMed PubMedCentral
  35.  
  36. Goldspink G. Tabary C, Tabary J.C., Tardien C, Tardien G. Effect of denervation on the adaptation of sarcomere number and muscle extensibility to func­tional length of the muscle . Ibid. 1974. 236. P. 733-742. CrossRef PubMed PubMedCentral
  37.  
  38. Grimby L., Hannerz J. Disturbance in voluntary recruitment order of low and high frequency motor units on blockades of proprioceptive afferent activity . Acta Physiol. Scand. 1976. 96. P. 207-216. CrossRef PubMed
  39.  
  40. Hansen J.W. Effects of repetitive stimulation on membrane potentials and twitch in human and rat in­tercostal muscle fibers . Ibid. 1974. 92. P. 238-248. CrossRef PubMed
  41.  
  42. Houston M.E., Bentzen H., Larsen H. Interrelation­ships between skeletal muscle adaptations and perfor­mance as studied by detraining and retraining . Ibid . 1979. 105. P. 163-170. CrossRef PubMed
  43.  
  44. JaweedM.M., NarayanP., Slopois J., Butler I. Iso­metric muscle force and fatigue changes is astronauts after 9 days of space flight. In: American congress of rehabilitation medicine. Washington DC, 1991. P.
  45.  
  46. Johnson M.A., Polgar J., Weightman D, Appleton D. Data on the distribution of fibre types in thirty-six human muscles. An autopsy study . J. Neurol. Sci. 1973. 18. P. 111-129. CrossRef  
  47. Koryak Yu. Contractile properties of the human tri­ceps surae muscle during simulated weightlessness . Eur. J. Appl. Physiol. 1995. 70. P. 344-350. CrossRef PubMed
  48.  
  49. Koryak Yu. Mechanical and electrical changes in «dry» immersion human muscle . Eur. J. Appl. Physiol. 1996. 74. P. 136-140. CrossRef PubMed
  50.  
  51. Koryak Yu., Siconolfi S.F., Kozlovskaya I.B., Gilbert J.H., Layne C.S. Maximal voluntary (MVC), tetanic (P ) and single twitch (P ) contractions before & after space flight . FASEB J. t- 1997. P. A1408.
  52.  
  53. Krnjevic K., Miledi R. Failure of neuromuscular propagation in rats . J. Physiol. 1958. 140. P. 440-461.
  54.  
  55. Lindstrom L., Kadefors R., Petersen I. An electromyo­graphic index for localized muscle fatigue . J. Appl. Physiol. 1977. 43. P. 750-754. CrossRef PubMed
  56.  
  57. Marsden CD., Meadows J.S., Merton P.A. Isolated single motor unit in human muscle and their rate of discharge during maximal voluntary effect . J. Physiol. 1971. 217. P. 12-13.
  58.  
  59. Mayer R.F., Burke R.E., Toop J., Hodgson J.A., Kan-da K., Walmsley B. The effect of long-term immobilization on the motor unit population of the cat medical gastrocnemius muscle . Neurosci. 1981. 6. P. 725-739. CrossRef  
  60. Merton P.A. Voluntary strength and fatigue . J. Physiol. 1954. 123. P. 553-564. CrossRef PubMed PubMedCentral
  61.  
  62. NaessK., Storm-MathissenA. Fatigue of sustained titanic contractions . Acta Physiol. Scand. 1955. 34. P. 351-356. CrossRef PubMed
  63.  
  64. Ranatunga K.W. Temperature-dependence of shorte­ning velocity and rate of isometric tension develop­ment in rat skeletal muscle . J. Physiol. 1982. 329. P. 465-483. CrossRef PubMed PubMedCentral
  65.  
  66. RiceC.L., Cunningham D.A., Taylor A.W., Pater-son D.H. Comparison of the histohemical and contractile properties of human triceps surae . Eur. J. Appl. Physiol. 1988. 58. P. 165-170. CrossRef PubMed
  67.  
  68. Sale D.G., McComas A.J., MacDougall J.D., Up­ton A.R.M. Neuromuscular adaptation in human th­enar muscles following strength training and immobi­lization . J. Appl. Physiol. 1982. 53. P. 419-424. CrossRef PubMed
  69.  
  70. Sandow A. Excitation-contraction coupling in skeletal muscle . Pharmacol. Rev. 1965. 17. P. 265-320.
  71.  
  72. SicaR.E.P., McComas A.J. An electrophysiological investigation of limb-girdle and facioscapulohumeral dystrophy . J. Neurol. Neurosur. Psychiat. 1971. 34. P. 469-474. CrossRef PubMed PubMedCentral
  73.  
  74. Siconolfi S.F., KozlovskayaI.B., Koryak Yu., Layne C, Gilbert J.H. Effects of in-flight treadmill & bicycle (TBE) and resistive (RE) exercise an post space flight strength . FASEB J. 1996. P. A1686.
  75.  
  76. Simmons R.M., Jewell B.R. Mechanics and models of muscular contraction . Res. Adv. Physiol. 1974. 9. P. 87-147.
  77.  
  78. Stevens L., MounierY., Holy X., Falempin M. Contractile properties of rat soleus muscle after 15 days of hindlimb suspension . J. Appl. Physiol. 1990. 68. P. 334-340. CrossRef PubMed
  79.  
  80. Tanaka M., McDonagh M.J.N., Davies G.T.M. A comparison of the mechanical properties of the first dorsal interosseous in the dominant and non-dominant hand . Eur. J. Appl. Physiol. 1984. 53. P. 17-20. CrossRef PubMed
  81.  
  82. TateC.A., Bick R.J., Muers T.D., Pitts B.J.R., van Winkle W.B., Entman M.L. Alteration of sarcoplas­mic reticulum after denervation of chicken pectoralis muscle . Biochem. J. 1983. 210. P. 339-344. CrossRef PubMed PubMedCentral
  83.  
  84. Upton A.R.M., McComas A.J., Sica R.E.P. Potentiation of "late" responses evoked in muscles during effort . J. Neurol, Neurosurg. Psychiat. 1971. 34. P. 113-120. CrossRef PubMed PubMedCentral
  85.  
  86. White M.J., Davies C.T.M., Brooksy P. The effects of shortterm voluntary immobilization on the contractile properties of the human triceps surae . Quart. J. Physiol. 1984. 69. P. 685-691. CrossRef PubMed
  87.  
  88. Witzmann F.A., Kim D.H., Fitts R.H. Hindlimb immobilization: length-tension and contractile prop­erties of skeletal muscle . J. Appl. Physiol. 1982. 53. P. 335-345. CrossRef PubMed
  89.  
  90. Woods F.F., Furbush F., Bigland-Ritchie B. Evidence for a fatigue-induced reflex inhibition of motoneuron firing rates . J. Neurophysiol. 1987. 58. P. 125-137. CrossRef PubMed

© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.