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Comparative characteristic of energy supply disturbances in arterial and venous walls of rabbits with alloxan diabetes and monoiodacetate intoxication
Ataman OV, Ataman IuO
Sumy Universuty of Ministry of Education and Science, Ukraine
DOI: https://doi.org/10.15407/fz57.02.043
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Abstract
We showed here that energy metabolism in thoracic rabbit aorta and posterior vena cava is disturbed two weeks following the induction of alloxan-induced diabetes and monoiod-acetate intoxication. In the vessels studied, the alterations are manifested in the decrease in the intensity of glucose uptake, oxygen consumption, lactic acid production, and ATP resynthesis. Simultaneously, the ATP content is significantly reduced. The possible significance of these disorders in the development of Monckeberg’s arteriosclerosis is discussed.
Keywords:
arteries, veins, alloxan diabetes, monoiodacetate,Monckeberg’s arteriosclerosis.
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