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ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2011; 57(1): 94-105

Influence of chronic emotional stress on the behaviour in "open field" test of rats with different level of motor activity

Shever'ova VM

    Research Institute of Biology, V.N. Karazin Kharkov National University, Ukraine


Experiments were carried out on 41 Wistar mail rats with body weight of 180 - 200 g. It was shown that in ‘open field’ the rats differed in the level of motional activity. Indepen­dently from level of locomotion investigated groups of rats were dissimilar at the criterions for “emotionality” and latent period of go out from the centr of “field”. Prolonged neurogen stress rendered various (modulating) influence on the behaviour of the rats in‘open field’ that was depended from their start level of activity. In the lowactive rats stress in the main acti­vated the motional and searching components of behaviour against a background of some decrease of the acts of defeca­tion. In the meanactive rats stress increased the freguency of rearing and strengthened excretion function and in the highactive of rats stress reduced the guantity of horizontal moving and lowered the thresholds of reactions of rats on the skin electri­cal stimulation, facilitated increase in these of rats the level of “emotionality”. Direction of changes of the time go out from the centr of “field” in each tested group basically depended by its start indexes and on peak of stress action had reverse de­pendence. It is supposed that changes of behaviour of rats in the “open field” under corresponding intensity of stress may be coused as by neuroendokrine changes as by stress damage of brain structures.

Keywords: “open field” test, motional activity, chronicalemotional stress.


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