Українська English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2010; 56(5): 53-61


Physiological aspects of analysis of the indexes of the variability of cardiac rhythm in adolescents with latent hypothyrosis

Voronych SM, Pavlykivs'ka BM, Voronych-Semchenko NM.

  1. Ivano-Frankivsk National Medical University, Ministry of Public Health of Ukraine
  2. Policlinic ¹2 of Desnyansky district of Kyiv, Ministry of Public Health of Ukraine
DOI: https://doi.org/10.15407/fz56.05.053


Abstract

We studied the parameters of variability of cardiac rhythm in adolescents with the latent hypothyrosis and in healthy individuals and the interrelationship of these parameters with the indexes of the thyroid system (hormonal status, dimensions of thyroid, median of ioduria). It has been revealed that iodine deprivation leads to vegetative dystonia with the decreased activity of the sympathetic nervous system. This is accompanied by the narrowing of the range of adaptive capabilities of the organism, exhaustion of the regulatory influences in comparison with healthy children. The analysis of the indexes of the variability of cardiac rhythm after the correction by iodide-100 detected the decrease of the influence of the parasympathetic nervous system on cardiac rhythm regulation and stabilization of the sympathetic component. The correlation link between the content of thyroid hormones and the indexes of the variability of cardiac rhythm has been determined. Such tendency proves the essential role of T3 and FT4 for the maintaining of the functional capability of Auto-nomic Nervous system in adolescents. The pathophysiologic patterns of vegetative profile of the variability of cardiac rhythm in latent hypothyrosys have been substantiated.

Keywords: variability of cardiac rhythm, latent hypothyrosis,thyroid status

References

  1. Amosova K.M., Konopl'ova L.F., Reshot'ko D.O. Variabel'nist' sertsevogo ritmu i ii zv'yazok z morfofunktsional'nim stanom pravogo shlunochka u hvorih na hronichne legeneve sertse vnaslidok hronichnogo obstruktivnogo zahvoryuvannya legen' . Ukr. pul'monol. zhurn. 2004. N3. S 33-36.
  2.  
  3. Baevskii P.M., Ivanov G.G., CHireikin L.V. analiz variabel'nosti serdechnogo ritma pri ispol'­zovanii razlichnih elektrokardiograficheskih sistem: Metod. rekomendatsii . Vestn. aritmologii.-2001. N24. S. 65-87.
  4.  
  5. Ganong V. F. Fiziologiya lyudini : Per. z ang. Nauk. red. perekladu M. Gzhegots'kii, V. SHevchuk, O.Zayachkivs'ka. L'viv: BaK, 2002. 784 s
  6.  
  7. Zelins'ka N.B., Reznikova a.L., Mamenko M.E. Zob u ditei: klinika, diferentsial'na diagnostika, likuvannya .Sovrem. pediatriya. 2006. N 1 (10). S. 57-65.
  8.  
  9. Kravchenko V.I., Tkachuk L.a., Turchin V.I. Osobli­vosti iodnoi zabezpechenosti naselennya Ukraini . Fiziol. zhurn. 2006. 52, N 2. S.190-191.
  10.  
  11. Maliani a. Fiziologicheskaya interpretatsiya spektral'nih komponentov variabel'nosti serdech-nogo ritma . Vestn. aritmologii. 1998. N 9. S.47-57.
  12.  
  13. Metodi izucheniya iododefitsitnih zabolevanii i monitoring ih ustraneniya. Rukovodstvo dlya menedzherov programm. 2-e izd. M., 2003. 430 s.
  14.  
  15. Nozdrachev A.D., Scherbatih YU.V. Sovremennie sposobi otsinki funktsional'nogo sostoyaniya avtonomnoi (vegetativnoi) nervnoi sistemi . Fiziologiya cheloveka. 2001. N 27. S. 95-101.
  16.  
  17. Mihailov V.M. Variabel'nost' ritma serdtsa. Opit prakticheskogo primeneniya. Izd. 2-e pererab. i dop. Ivanovo, 2002. 289 s.
  18.  
  19. Mihailov V.M., Fil'kina O.M., SHanina T.G. Predeli fiziologicheskoi normi parametrov variabel'nosti serdechnogo ritma zdorovih pod­rostkov 14-16 let v zavisimosti ot pola i urovnya trenovannosti . Ul'trazvukovaya i funktsional'naya diagnostika. 2009. N 3. S. 67-73.
  20.  
  21. Pan'kiv V.I. Ioddefitsitni zahvoryuvannya: Prak­tichnii posibnik. K., 2003. 72 s.
  22.  
  23. Teppermen Dzh., Teppermen X. Fiziologiya obmena veschestv i endokrinnoi sistemi . M.: Mir, 1989. S. 274-314.
  24.  
  25. Tireoidnii status i serdechno-sosudistaya sistema . Ros. med. vesti. 2000. N1. S. 18-25.
  26.  
  27. Fiziologiya cheloveka: V 3-h tomah. T.2. Per. s angl. / Pod red. R. SHmidta i G. Tevsa. M.: Mir, 1996. 313 s.
  28.  
  29. Shidlovs'kii V.O., Deikalo I.M., SHidlovs'kii O.V. Iododefitsitni zahvoryuvannya: diagnostika, liku­vannya, profilaktika. Ternopil': Ukrmedkniga, 2006. 84 s
  30.  
  31. Bernal J., Nunez J. Thyroid hormones and brain development . Eur. J. Endocrinol. 1995. 133. P. 390-398. CrossRef PubMed
  32.  
  33. Delong G.R., Robbins J., Condliffe P.O. Iodine and the brain. New York, 1989. 287 p. CrossRef  
  34. Dunn J., Grutchfield H., Gutekunst R. Two simple metods for measuring iodine in urine . Thyroid. 1993. 3 P.119-123. 19. The Task force of the european society of cardiology the north american society of pacing Electrophysiol-ogy. Heart Rate Variability: Standards of Measurement, Physiological Interpretation, and clinical use. Circulation. 1996. 93. P.1043-1065.
  35.  
  36. Zimmermann M.B., Hess S.Y., Molinari L. New refer-encevalues for thyroid volume by ultrasound iniodine-sufficient schoolchildren: a word health organization . Amer. J. Clin. Nutrit. 2004. 79, N 2. P. 231-237. CrossRef PubMed
  37.  

© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.