Alteration of calcium signaling as one of the mechanisms of Alzheimer's disease and diabetic polyneuropathy
Kostiuk OP, Korol' TIu, Korol' SV, Romanenko SV, Pinchenko VO, Kostiuk PH
O.O.Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz56.04.130
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Abstract
This review is devoted to the action of amyloid-b peptide on the functional activity of intracellular and plasmalemmal calcium-regulated structures in cultured hyppocampal neurons: mitochondria and voltage-gated calcium channels. A comparative analysis of relative changes of plasmalemmal structures in such neurodegenerative diseases as Alzheimer’s illness and diabetic neuropathy has been made.
Keywords:
mitochondrion, Alzheimers disease, diabetic neuropathy, neurodegenerative disease, neurons, hippocampus, plasmalemal calcium channels, calcium.
References
- Kostyuk P.G., Zima V.L., Magura I.C., Miroshnichenko M.S., Shuba M.F. Biofizika. K.: Oberegi, 2008. 544 c.
- Yahno N.N., Preobrazhenskaya I.S. Bolezn' Al'ts-geimera: patogenez, klinika, lechenie . Rus. med.zhurn. 2002. 10. P. 1143-1146.
- Anand U., Otto W.R., Casula M.A., Day N.C., Davis J.B., Bountra C., Birch R.,Anand P. The effect of neurotrophic factors on morphology, TRPV1 expression and capsaicin responses of cultured human DRG sensory neurons . Neurosci.Lett. 2006. 399. P. 51-56.
CrossRef
PubMed
- Arispe N., Rojas E.,Pollard H.B. Alzheimer disease amyloid beta protein forms calcium channels in bi-layer membranes: blockade by tromethamine and aluminum . Proc.Natl.Acad.Sci.USA. 1993. 90. P. 567-571.
CrossRef
PubMed PubMedCentral
- Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D.Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway . Nature. 1997. 389. P. 816-824.
CrossRef
PubMed
- Cesare P., McNaughton P. A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin . Proc.Natl.Acad.Sci.USA. 1996. 93. P. 15435-15439.
CrossRef
PubMed PubMedCentral
- Clapham D.E. TRP channels as cellular sensors . Nature. 2003. 426. P. 517-524.
CrossRef
PubMed
- Cook D.G., Li X., Cherry S.D.,Cantrell A.R. Presenilin 1 deficiency alters the activity of voltage-gated Ca2+ channels in cultured cortical neurons . J.Neurophysiol. 2005. 94. P. 4421-4429.
CrossRef
PubMed
- Davidson R.M., Shajenko L.,Donta T.S. Amyloid beta-peptide (A beta P) potentiates a nimodipine-sensitive L-type barium conductance in N1E-115 neuroblastomacells . Brain Res. 1994. 643. P. 324-327.
CrossRef
- Hooper N.M. Alzheimer's disease: methods and protocols.: Humana press Inc, 2002.
- Furukawa K., Abe Y.,Akaike N. Amyloid beta protein-induced irreversible current in rat cortical neurones . Neuroreport. 1994. 5. P. 2016-2018.
CrossRef
PubMed
- Gibson G.E., Sheu K.F.,Blass J.P. Abnormalities of mitochondrial enzymes in Alzheimer disease . J.Neural Transm. 1998. 105. P. 855-870.
CrossRef
PubMed
- He L.M., Chen L.Y., Lou X.L., Qu A.L., Zhou Z.,Xu T. Evaluation of beta-amyloid peptide 25-35 on calcium homeostasis in cultured rat dorsal root ganglion neurons . Brain Res. 2002. 939. P. 65-75.
CrossRef
- Hirai K., Aliev G., Nunomura A., Fujioka H., Russell R.L., Atwood C.S., Johnson A.B., Kress Y. , Vinters H.V., Tabaton M., Shimohama S., Cash A.D., Siedlak S.L., Harris P.L., Jones P.K., Petersen R.B., Perry G.,Smith M.A. Mitochondrial abnormalities in Alzheimer's disease . J.Neurosci. 2001. 21. P. 3017-3023.
CrossRef
PubMed PubMedCentral
- Hu H.J., Bhave G.,Gereau R.W. Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia . J.Neurosci. 2002. 22. P. 7444-7452.
CrossRef
PubMed PubMedCentral
- Kang J., Lemaire H.G., Unterbeck A., Salbaum J.M., Masters C.L., Grzeschik K.H., Multhaup G., Beyreuther K.,Muller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor . Nature. 1987. 325. P. 733-736.
CrossRef
PubMed
- Kawahara M., Kuroda Y. Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: channel formation and disruption of calcium homeostasis . Brain Res.Bull. 2000. 53. P. 389-397.
CrossRef
- Kim B.M., Lee S.H., Shim W.S.,Oh U. Histamine-in-duced Ca(2+) influx via the PLA(2). lipoxygenase. TRPV1 pathway in rat sensory neurons . Neurosci. Lett. 2004. 361. P. 159-162.
CrossRef
PubMed
- Korol' T.I., Kostiuk O.P.,Kostiuk P.H. Effect of beta-amyloid protein on calcium channels in plasma membranes of cultured hippocampal neurons . Fiziol.Zh. 2009. 55. P. 10-16.
- Leissring M.A., Paul B.A., Parker I., Cotman C.W.,LaFerla F.M. Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes . J.Neurochem. 1999. 72. P. 1061-1068.
CrossRef
PubMed
- Li W.Y., Butler J.P., Hale J.E., McClure D.B., Little S.P., Czilli D.L.,Simmons L.K. Suppression of an amyloid beta peptide-mediated calcium channel response by a secreted beta-amyloid precursor protein . Neuroscience. 2000. 95. P. 1-4.
CrossRef
- Lopshire J.C., Nicol G.D. The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: whole-cell and single-channel studies . J.Neurosci. 1998. 18. P. 6081-6092.
CrossRef
PubMed PubMedCentral
- Marinelli S., Vaughan C.W., Christie M.J.,Connor M. Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus in vitro . J.Physiol. 2002. 543. P. 531-540.
CrossRef
PubMed PubMedCentral
- Mark R.J., Pang Z., Geddes J.W., Uchida K.,Mattson M.P. Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation . J.Neurosci. 1997. 17. P. 1046-1054.
CrossRef
PubMed PubMedCentral
- Masters C.L., Simms G., Weinman N.A., Mult-haup G., McDonald B.L.,Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome . Proc.Natl.Acad.Sci.USA. 1985. 82. P. 4245-4249.
CrossRef
PubMed PubMedCentral
- Moriyama T., Higashi T., Togashi K., Iida T., Segi E., Sugimoto Y., Tominaga T., Narumiya S.,Tominaga M. Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins . Mol.Pain. 2005. 1. P. 3.
CrossRef
PubMed PubMedCentral
- Nilius B., Owsianik G., Voets T.,Peters J.A. Transient receptor potential cation channels in disease . Physiol Rev. 2007. 87. P. 165-217.
CrossRef
PubMed
- Pabbidi R.M., Yu S.Q., Peng S., Khardori R., Pauza M.E.,Premkumar L.S. Influence of TRPV1 on diabetes-induced alterations in thermal pain sensitivity . Mol.Pain. 2008. 4. P. 9.
CrossRef
PubMed PubMedCentral
- Pegorini S., Braida D., Verzoni C., Guerini-Rocco C., Consalez G.G., Croci L.,Sala M. Capsaicin exhibits neuroprotective effects in a model of transient global cerebral ischemia in Mongolian gerbils . Brit.J.Pharmacol. 2005. 144. P. 727-735.
CrossRef
PubMed PubMedCentral
- Ramsden M., Henderson Z.,Pearson H.A. Modulation of Ca2+ channel currents in primary cultures of rat cortical neurones by amyloid beta protein (1-40) is dependent on solubility status . Brain Res. 2002. 956. P. 254-261.
CrossRef
- Resende R., Pereira C., Agostinho P., Vieira A.P., Malva J.O.,Oliveira C.R. Susceptibility of hippocampal neurons to Abeta peptide toxicity is associated with perturbation of Ca2+ homeostasis .Ibid. 2007. 1143. P. 11-21.
CrossRef
PubMed
- Rizzuto R., Brini M., Murgia M.,Pozzan T. Micro-domains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria . Science. 1993. 262. P. 744-747.
CrossRef
PubMed
- Romanenko S.V., Kostyuk E.P., Kostyuk P.G. Specificity of gabapentin action in different populations of dorsal root ganglion neurons of rats with streptozotocin-induced diabetes . Neurophysiology. 2009. 41. P. 119-130.
CrossRef
- van der S.M., Di M., V. Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels . Eur.J.Biochem. 2004. 271. P. 1827-1834.
CrossRef
PubMed
- Veldhuis W.B., van der S.M., Wadman M.W., van Z.G.,Maccarrone M., Fezza F., Veldink G.A., Vliegenthart J.F., Bar P.R., Nicolay K.,Di M., V. Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases . J.Neurosci. 2003. 23. P. 4127-4133.
CrossRef
PubMed PubMedCentral
- Voets T., Droogmans G., Wissenbach U., Janssens A., Flockerzi V.,Nilius B. The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels . Nature. 2004. 430. P. 748-754. 37. Webster S., Bradt B., Rogers J.,Cooper N. Aggregation state-dependent activation of the classical complement pathway by the amyloid beta peptide . J.Neurochem. 1997. 69. P. 388-398.
CrossRef
PubMed
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