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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

(English title: Physiological Journal)

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2010; 56(4): 130-138


Alteration of calcium signaling as one of the mechanisms of Alzheimer's disease and diabetic polyneuropathy

Kostiuk OP, Korol' TIu, Korol' SV, Romanenko SV, Pinchenko VO, Kostiuk PH

    O.O.Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz56.04.130


Abstract

This review is devoted to the action of amyloid-b peptide on the functional activity of intracellular and plasmalemmal calcium-regulated structures in cultured hyppocampal neurons: mitochondria and voltage-gated calcium channels. A comparative analysis of relative changes of plasmalemmal structures in such neurodegenerative diseases as Alzheimer’s illness and diabetic neuropathy has been made.

Keywords: mitochondrion, Alzheimer’s disease, diabetic neuropathy, neurodegenerative disease, neurons, hippocampus, plasmalemal calcium channels, calcium.

References

  1. Kostyuk P.G., Zima V.L., Magura I.C., Miroshnichenko M.S., Shuba M.F. Biofizika. K.: Oberegi, 2008. 544 c.
  2.  
  3. Yahno N.N., Preobrazhenskaya I.S. Bolezn' Al'ts-geimera: patogenez, klinika, lechenie . Rus. med.zhurn. 2002. 10. P. 1143-1146.
  4.  
  5. Anand U., Otto W.R., Casula M.A., Day N.C., Davis J.B., Bountra C., Birch R.,Anand P. The effect of neurotrophic factors on morphology, TRPV1 expres­sion and capsaicin responses of cultured human DRG sensory neurons . Neurosci.Lett. 2006. 399. P. 51-56. CrossRef PubMed
  6.  
  7. Arispe N., Rojas E.,Pollard H.B. Alzheimer disease amyloid beta protein forms calcium channels in bi-layer membranes: blockade by tromethamine and aluminum . Proc.Natl.Acad.Sci.USA. 1993. 90. P. 567-571. CrossRef PubMed PubMedCentral
  8.  
  9. Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D.Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway . Na­ture. 1997. 389. P. 816-824. CrossRef PubMed
  10.  
  11. Cesare P., McNaughton P. A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin . Proc.Natl.Acad.Sci.USA. 1996. 93. P. 15435-15439. CrossRef PubMed PubMedCentral
  12.  
  13. Clapham D.E. TRP channels as cellular sensors . Na­ture. 2003. 426. P. 517-524. CrossRef PubMed
  14.  
  15. Cook D.G., Li X., Cherry S.D.,Cantrell A.R. Presenilin 1 deficiency alters the activity of voltage-gated Ca2+ channels in cultured cortical neurons . J.Neurophysiol. 2005. 94. P. 4421-4429. CrossRef PubMed
  16.  
  17. Davidson R.M., Shajenko L.,Donta T.S. Amyloid beta-peptide (A beta P) potentiates a nimodipine-sensitive L-type barium conductance in N1E-115 neuroblastomacells . Brain Res. 1994. 643. P. 324-327. CrossRef.1016/0006-8993(94)90041-8
  18.  
  19. Hooper N.M. Alzheimer's disease: methods and pro­tocols.: Humana press Inc, 2002.
  20.  
  21. Furukawa K., Abe Y.,Akaike N. Amyloid beta protein-induced irreversible current in rat cortical neurones . Neuroreport. 1994. 5. P. 2016-2018. CrossRef PubMed
  22.  
  23. Gibson G.E., Sheu K.F.,Blass J.P. Abnormalities of mitochondrial enzymes in Alzheimer disease . J.Neural Transm. 1998. 105. P. 855-870. CrossRef PubMed
  24.  
  25. He L.M., Chen L.Y., Lou X.L., Qu A.L., Zhou Z.,Xu T. Evaluation of beta-amyloid peptide 25-35 on calcium homeostasis in cultured rat dorsal root gan­glion neurons . Brain Res. 2002. 939. P. 65-75. CrossRef.1016/S0006-8993(02)02549-0
  26.  
  27. Hirai K., Aliev G., Nunomura A., Fujioka H., Russell R.L., Atwood C.S., Johnson A.B., Kress Y. , Vinters H.V., Tabaton M., Shimohama S., Cash A.D., Siedlak S.L., Harris P.L., Jones P.K., Petersen R.B., Perry G.,Smith M.A. Mitochondrial abnormalities in Alzheimer's disease . J.Neurosci. 2001. 21. P. 3017-3023. CrossRef PubMed PubMedCentral
  28.  
  29. Hu H.J., Bhave G.,Gereau R.W. Prostaglandin and pro­tein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia . J.Neurosci. 2002. 22. P. 7444-7452. CrossRef PubMed PubMedCentral
  30.  
  31. Kang J., Lemaire H.G., Unterbeck A., Salbaum J.M., Masters C.L., Grzeschik K.H., Multhaup G., Beyreuther K.,Muller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor . Nature. 1987. 325. P. 733-736. CrossRef PubMed
  32.  
  33. Kawahara M., Kuroda Y. Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amy­loid protein: channel formation and disruption of calcium homeostasis . Brain Res.Bull. 2000. 53. P. 389-397. CrossRef.1016/S0361-9230(00)00370-1
  34.  
  35. Kim B.M., Lee S.H., Shim W.S.,Oh U. Histamine-in-duced Ca(2+) influx via the PLA(2). lipoxygenase. TRPV1 pathway in rat sensory neurons . Neurosci. Lett. 2004. 361. P. 159-162. CrossRef PubMed
  36.  
  37. Korol' T.I., Kostiuk O.P.,Kostiuk P.H. Effect of beta-amyloid protein on calcium channels in plasma membranes of cultured hippocampal neurons . Fiziol.Zh. 2009. 55. P. 10-16.
  38.  
  39. Leissring M.A., Paul B.A., Parker I., Cotman C.W.,LaFerla F.M. Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes . J.Neurochem. 1999. 72. P. 1061-1068. CrossRef PubMed
  40.  
  41. Li W.Y., Butler J.P., Hale J.E., McClure D.B., Little S.P., Czilli D.L.,Simmons L.K. Suppression of an amy­loid beta peptide-mediated calcium channel response by a secreted beta-amyloid precursor protein . Neuroscience. 2000. 95. P. 1-4. CrossRef.1016/S0306-4522(99)00479-0
  42.  
  43. Lopshire J.C., Nicol G.D. The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: whole-cell and single-channel studies . J.Neurosci. 1998. 18. P. 6081-6092. CrossRef PubMed PubMedCentral
  44.  
  45. Marinelli S., Vaughan C.W., Christie M.J.,Connor M. Capsaicin activation of glutamatergic synaptic trans­mission in the rat locus coeruleus in vitro . J.Physiol. 2002. 543. P. 531-540. CrossRef PubMed PubMedCentral
  46.  
  47. Mark R.J., Pang Z., Geddes J.W., Uchida K.,Mattson M.P. Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation . J.Neurosci. 1997. 17. P. 1046-1054. CrossRef PubMed PubMedCentral
  48.  
  49. Masters C.L., Simms G., Weinman N.A., Mult-haup G., McDonald B.L.,Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome . Proc.Natl.Acad.Sci.USA. 1985. 82. P. 4245-4249. CrossRef PubMed PubMedCentral
  50.  
  51. Moriyama T., Higashi T., Togashi K., Iida T., Segi E., Sugimoto Y., Tominaga T., Narumiya S.,Tominaga M. Sensitization of TRPV1 by EP1 and IP reveals periph­eral nociceptive mechanism of prostaglandins . Mol.Pain. 2005. 1. P. 3. CrossRef PubMed PubMedCentral
  52.  
  53. Nilius B., Owsianik G., Voets T.,Peters J.A. Transient receptor potential cation channels in disease . Physiol Rev. 2007. 87. P. 165-217. CrossRef PubMed
  54.  
  55. Pabbidi R.M., Yu S.Q., Peng S., Khardori R., Pauza M.E.,Premkumar L.S. Influence of TRPV1 on diabe­tes-induced alterations in thermal pain sensitivity . Mol.Pain. 2008. 4. P. 9. CrossRef PubMed PubMedCentral
  56.  
  57. Pegorini S., Braida D., Verzoni C., Guerini-Rocco C., Consalez G.G., Croci L.,Sala M. Capsaicin ex­hibits neuroprotective effects in a model of transient global cerebral ischemia in Mongolian gerbils . Brit.J.Pharmacol. 2005. 144. P. 727-735. CrossRef PubMed PubMedCentral
  58.  
  59. Ramsden M., Henderson Z.,Pearson H.A. Modulation of Ca2+ channel currents in primary cultures of rat cortical neurones by amyloid beta protein (1-40) is dependent on solubility status . Brain Res. 2002. 956. P. 254-261. CrossRef.1016/S0006-8993(02)03547-3
  60.  
  61. Resende R., Pereira C., Agostinho P., Vieira A.P., Malva J.O.,Oliveira C.R. Susceptibility of hippocampal neurons to Abeta peptide toxicity is associated with perturbation of Ca2+ homeostasis .Ibid. 2007. 1143. P. 11-21. CrossRef PubMed
  62.  
  63. Rizzuto R., Brini M., Murgia M.,Pozzan T. Micro-domains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria . Science. 1993. 262. P. 744-747. CrossRef PubMed
  64.  
  65. Romanenko S.V., Kostyuk E.P., Kostyuk P.G. Specific­ity of gabapentin action in different populations of dor­sal root ganglion neurons of rats with streptozotocin-induced diabetes . Neurophysiology. 2009. 41. P. 119-130. CrossRef
  66.  
  67. van der S.M., Di M., V. Endovanilloids. Putative en­dogenous ligands of transient receptor potential vanilloid 1 channels . Eur.J.Biochem. 2004. 271. P. 1827-1834. CrossRef PubMed
  68.  
  69. Veldhuis W.B., van der S.M., Wadman M.W., van Z.G.,Maccarrone M., Fezza F., Veldink G.A., Vliegenthart J.F., Bar P.R., Nicolay K.,Di M., V. Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases . J.Neurosci. 2003. 23. P. 4127-4133. CrossRef PubMed PubMedCentral
  70.  
  71. Voets T., Droogmans G., Wissenbach U., Janssens A., Flockerzi V.,Nilius B. The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels . Nature. 2004. 430. P. 748-754. 37. Webster S., Bradt B., Rogers J.,Cooper N. Aggregation state-dependent activation of the classical complement pathway by the amyloid beta peptide . J.Neurochem. 1997. 69. P. 388-398. CrossRef PubMed

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