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The effect of initial hormonal status of recipient animals on morphological state and endocrine function of ovarian tissue transplant
Kiroshka VV, Tishchenko IuO
- Institute for Problems of Cryobiology and Cryomedicine ofthe National Academy of Sciences of Ukraine, Kharkov, Ukraine
- V.N. Karazin’s Kharkov National University, Ukraine
DOI: https://doi.org/10.15407/fz56.04.121
Abstract
The aim of investigation was a comparative analysis of morpho-functional characteristics of allografts of mature ovarian tissue and neonatal ovary depending on initial hormonal status of recipient animals. Rats’ mature ovarian tissue and neonatal ovary were transplanted under renal capsule simultaneously with ovariectomy and 2 months later. Data analysis indicated that the development of ovarian tissue transplant was determined by its maturity and initial hormonal status of recipient. Mature ovarian tissue transplants preserve morphology and endocrine function to the 60th day after transplantation to the recipient animals with the initial hormonal status that corresponds to the norm. Neonatal ovary transplants are developed to the mature stage following transplantation to recipients with hormonal status that corresponded to the ova-riectomized animals, that is, low concentration of sex hormones and an increased level of follicle-stimulating hormone.
Keywords:
ovary, transplantation, ovariectomy, recipient, follicle-stimulating hormone.
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