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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2010; 56(4): 121-129


THE EFFECT OF INITIAL HORMONAL STATUS OF RECIPIENT ANIMALS FOR MORPHOLOGICAL STATE AND ENDOCRINE FUNCTION OF OVARIAN TISSUE TRANSPLANT

V.V. Kiroshka, J.O. Tischenko

    Institute for Problems of Cryobiology and Cryomedicine ofthe National Academy of Sciences of Ukraine,Kharkov;V.N. Karazin’s Kharkov National University


Abstract

The aim of investigation was a comparative analysis of morpho-functional characteristics of allografts of mature ovarian tissue and neonatal ovary depending on initial hormonal status of recipient animals. Rats’ mature ovarian tissue and neonatal ovary were transplanted under renal capsule simultaneously with ovariectomy and 2 months later. Data analysis indicated that the development of ovarian tissue transplant was deter­mined by its maturity and initial hormonal status of recipient. Mature ovarian tissue transplants preserve morphology and endocrine function to the 60th day after transplantation to the recipient animals with the initial hormonal status that corresponds to the norm. Neonatal ovary transplants are de­veloped to the mature stage following transplantation to recipients with hormonal status that corresponded to the ova-riectomized animals, that is, low concentration of sex hormones and an increased level of follicle-stimulating hormone.

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