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Calcium ions in cell nucleus
Kostiuk PH
Bogomoletz Institute of physiology NAS of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz56.04.010
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Abstract
Cell nuclei have a complex shell structure that shields the genetic apparatus from the rest of the cytoplasm. It consists of two membranes outer and inner between which is the cavity of the perinuclear space. Importantly, the latter is associated with the lumen of the endoplasmic reticulum (ER) due to the fact that the membrane of the EP is morphologically conjugated to the outer membrane of the nucleus; therefore, perinuclear space can be considered as a specific part of the ER.
Keywords:
calcium, nucleus
References
- Fedorenko O.A., Duzhii D.Ie., Marchenko SM. Kationni kanali velikoi providnosti v yadernii obolontsi neironiv Purkin'ie mozochka shchuriv . Neirofiziologiya. Neurophysiology 2007. 39, N 3. S 13-18.
CrossRef
- Bading H., Ginty D.D., Greenberg M.E. Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways . Science. 1993. 260. P. 181-186.3. Birch B.D., Eng D.L., Kocsis J.D. Intranuclear Ca2+ transients during neurite regeneration of an adult mammalian neuron . Proc. Nat. Acad. Sci. USA. 1993. 89. P. 7978-7982.
CrossRef
PubMed
- Fedorenko O.A., Duzhyy D.?.E?, Marchenko S.?M. Ca2+ channels in the nuclear membrane of hippocam-pal pyramidal neurons . Acta Physiol. 2006. P. 183-186.
- Gerasimenko O.V., Gerasimenko J.V., Tepikin A.V., Petersen O.H. ATP-dependent accumulation and inositol trisphosphate- or cyclic ADP-ribose-mediated release of Ca2+ from the nuclear envelope . Cell. 1995. 80. P. 439-444.
CrossRef
- Holliday J., Adams R.J., Sejnowski T.J., Spitzer N.C. Calcium-induced release of calcium regulates differentiation of cultured spinal neurons . Neuron. 1991. 7. p. 787-796.
CrossRef
- Humbert J.P., Matter N., Artault J.C., Koppler P., Malviya A.N. Inositol 1,4,5-trisphosphate receptor is located to the inner nuclear membrane vindicating regulation of nuclear calcium signaling by inositol 1,4,5-trisphosphate. Discrete distribution of inositol phosphate receptors to inner and outer nuclear membranes . J. Biol. Chem. 1996. 271. P. 478-485.
CrossRef
PubMed
- Roche E., Prentki M. Calcium regulation of immediate-early response genes . Cell. Calcium. 1994. 16. P 331-338.
CrossRef
- Utzschneider D.A., Rand M.N., Waxman S.G., Kocsis J.D. Nuclear and cytoplasmic Ca2+ signals in developing rat dorsal root ganglion neurons studied in excised tissue . Brain. Res. 1994. 635. P. 231-237.
CrossRef
- Werlen G., Belin D., Conne B., Roche E., Lew D.P., Prentki M. Intracellular Ca2+ and the regulation of early response gene expression in HL-60 myeloid leukemia cells . J. Biol. Chem. 1993. 268. P. 16596-16601.
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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.
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