Українська Русский English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2009; 55(6): 48-54


The behavioral features in mice induced by somatic and visceral pain underinfluence of short immobilization stress

B. S. Sushko

    Ін-т фізіології ім. О. Богомольця НАН України, Київ


Abstract

In experiments on mice with behavior registration, we investigated the influence of short (30 min) immobilization stress on the development of somatic (the formalin test) and visceral (the acetic test) pain. It is shown that during somatic pain short immobilization prolongs the duration of the initial sharp and the remote phases of painful reaction. This is ac­companied by an increase in motion activity and reduction of sleep duration. When visceral pain was evoked, such stress causes occurrence of the period of temporal hyperalgesia to­gether with activation of mobility of animals.

References

  1. Березовский В. Я., Костюк П. Г., Мойбенко О. О. Ганс Селье - лікар, патофізіолст, гуманіст (1907-1982) //Фізіол. журн. - 2007. - 53, №3. -С. 94-102.
  2. Будак А.В., Сушко Б.С. Гиперальгезивное влияние эмоционального стресса у мышей линий C57BL/6J и CBA/CaLac на фоне заданного суточного ритма // Нейрофизиология/Neurophysiology. - 2006. - 38, № 5/6. -С. 466-471.
  3. Лиманский Ю. П., Тамарова 3. А., Бидков Е. Г., Колбун Н. Д. Угнетение ноцицептивных реакций мышей под влиянием низкоинтенсивного микро­волнового облучения точек акупунктуры // Нейрофизиология / Neurophysiol. - 1999. - 31, №. 4. -С. 318-322.
  4. Про захист тварин від негуманного поводження // Закон України № 3447-IV від 21 лютого 2006 p. - Відомості Верховної Ради України. - 2006. - 27. - 990 с
  5. Селье Г. Очерки об адаптационном синдроме. - М.: Медгиз, 1960. - 254 с
  6. Сушко Б. С Особливості больової реакції та чутливості тварин різних генетичних груп // Фізіол. журн. - 2004. - 50, № 2. - C. 75-79.
  7. Сушко Б. С Розвиток вісцерального болю під впли-вом ноцицептивного стимулу і генетичного фактора // Фізіол. журн. - 2006. - 52, № 3. - С 78-83.
  8. Bessinre B., RicheM P., Laboureyras E. et al. Nitrous oxide (N2O) prevents latent pain sensitization and long-term anxiety-like behavior in pain and opioid-experi-enced rats // Neuropharmacol. - 2007. - 53, № 6. -P. 733-740.
  9. 9. Bhattacharya S. K., Das N., Sarkar M. K. Inhibition of carrageenin-induced pedal oedema in rats by immobili­sation stress // Res. Exp. Med. - 1987. - 187, № 4. -P 303-313
  10. 10. Bocheva A.I., Djambazova E.B. Immobilization, cold and hot stresses temperature and nociceptive changes in rats: comparative study // Acta Physiologica. - 2007. -191, Suppl. 658. - P. F19-158.
  11. Chakrabart K., Chakrabart A.S., Mahaja A.S., Mishr T.K. Immobilisation stress induced analgesia in dia­betic rats // Indian J. Physiol. Pharmacol. - 1997. - 41, №3. - P. 275-279.
  12. Chu L.F., Angst M.S., Clark D. Opioid-induced hype­ralgesia in humans: molecular mechanisms and clinical considerations // Clin J. Pain. - 2008. - 24, № 6. -P. 479-496.
  13. Chuyan E. N., Zayachnikova T. V. Hypokinetic stress-Induced modifications of the pain sensitivity in rats // Neirofiziologiya/Neurophysiology. - 2007. - 39, № 2. -P. 174-183.
  14. Croissandeaua G., Wahnonb F., Yashpalb K., Nabil G. Increased stress-induced analgesia in mice lacking the proneuropeptide convertase PC2 // Neuroscience Letters. - 2006. - 406, Issues 1-2. - P. 71-75.
  15. DuPen A., Shen D., Ersek M. Mechanisms of opioid-induced tolerance and hyperalgesia // Pain Manag. Nurs. -2007. - 8, №3. - P. 113-121.
  16. Gebhart G. F., Joshi S. K. Visceral pain // Current Rev. Pain. - 2000. - 4, № 6. - P. 499-506.
  17. Hwang B.H., Chang H.M., Gu Z.H., Suzuki R. C-fos gene expression is increased in the paraventricular hy­pothalamic nucleus of Sprague-Dawley rats with vis­ceral pain induced by acetic acid without detectable changes of corticotrophin-releasing factor mRNA: a quantitative approach with an image analysis system // Anat. Rec. (Hoboken). - 2007. - 290, № 4. - P. 406-413.
  18. Imbe H., H. Iwai-Liao H., Senba E. Stress-inducedhyperalgesia: animal models and putative mechanisms // Front Biosci. - 2006. - 11, № 1. - P. 2179-2192.
  19. 19. Kiiatkin EA. The pain sensitivity and behavioral reactivity of rats in somatic and visceral pain states // Izv. Akad. Nauk SSSR Biol. - 1990. - Jul-Aug, 4. - P. 632-635.
  20. 20. Kwon M.S., Seo Y.J., Shim E.J., Lee J.K. et al. The differential effects of emotional or physical stress on pain behaviors or on c-Fos immunoreactivity in paraventricular nucleus or arcuate nucleus // Brain Res. -2008. - 1190, №23. - P. 122-131.
  21. Limansky Y. P., Tamarova Z. A., Gulyar S. A. Suppression of pain by exposure of acupuncture points to polarized light // Pain Res. Menage. - 2006. - 11, № 1. - P. 49-57.
  22. Marin M.T., Cruz F.C., Planeta C.S. Chronic restraint or variable stresses differently affect the behavior, corticosterone secretion and body weight in rats // Physiol. Behav. - 2007. - 90, № 1. - P. 29-35.
  23. Mineta K., Nomura M., Terado M. et al. Upregulation of corticotropin-releasing hormone gene expression in the paraventricular nucleus of cyclophosphamide-in-duced cystitis in male rats // Brain Res. - 2004. - 1018, №2. - P. 193-200.
  24. Porro C.A., Carli G. Immobilization and restraint ef­fects on pain reactions in animals // Pain. - 1988. - 32, № 3. - P. 289-307.
  25. Rivat C, Laboureyras E., Laulin J.P. et al. Non-nociceptive environmental stress induces hyperalge­sia, not analgesia, in pain and opioid-experienced rats // Neuropsychopharmacol. - 2007. - 32, № 10. -P. 2217-2228.
  26. Robinson D. A., Wei F., Wang G. D. et al. Oxytocin mediates stress-induced analgesia in adult mice // J. Physiol. - 2002. - 540, № 2. - P. 593-606.
  27. Seo Y.J., Kwon M.S., Shim E.J. et al. Changes in pain behavior induced by formalin, substance P, glutamate and pro-inflammatory cytokines in immobilization-in­duced stress mouse model // Brain Res. Bull. - 2006. -71, № 1-3. - P. 279-286.

© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2019.