Українська Русский English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2009; 55(6): 41-47


HISTOLOGICAL AND HORMONAL CHARACTERISTIC OF MICROENCAPSULATED HUMAN PARATHYROID TISSUE IN LONG-TERM CULTURE

I.P.Pasteur, I.A.Balla, A.Ye. Kovalenko, M.D.Tronko

    State Institution V.P. Komisarenko Institute of Endocrinology and Metabolism of the AMS of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz55.06.041

Abstract

Microencapsulated human parathyroid tissue preserves the viability and high ability to secrete parathormone in long-term culture that indicates on perspective to further study the efficiency of using this tissue in the presence of compensated hypofunctional state of parathyroid system in experimental animals.

Keywords: Parathyroid, microencapsulation, cultivation, histology, parathormone.

References

  1. Paster І.P. Funktsіonal'na harakteristika mіkroіn-kapsul'ovanoї tkanini adenomi paraschitovidnoї zalozi lyudini v umovah in vitro . Dop. HAH Ukraїni. - 2007.  ; 9.  S. 174-179.
  2. Arlt W., Fremerey C., Callies F. et al. Well-being, mood and calcium homeostasis in patients with hypopara¬thyroidism receiving standard treatment with calcium and vitamin D . Eur. J. Endocrinol. 2002. 146(2). 215-222. CrossRef PubMed
  3.  
  4. Bohrer T., Pasteur I., Lyutkevych O. et al. Permanenter hypoparathyreoidismus infolge von schilddrusenkarzi-nomoperationen nach Tschernobyl in der Ukraine . Dtsch. Med. Wochenschr. 2005. 130(44). 2501-2506. CrossRef PubMed
  5.  
  6. Brown A.J., Zhong M., Ritter C. et al. Loss of calcium responsiveness in cultured bovine parathyroid cells is associated with decreased calcium receptor expression . Biocem. Biophis. Res. Commun. 1995. 212 (3). 861-867. CrossRef PubMed
  7.  
  8. Chang S.J., Lee C.H., Hsu C.Y. and Wang Y.J. Biocompatible microcapsules with enhanced mechani¬cal strength . J. Biomed. Mater. Res. 2002. 59 (1). 118-126. CrossRef PubMed
  9.  
  10. De Vos P., Hamel A.F., Tatarkiewicz K. Considerations for successful transplantation of encapsulated pancre¬atic islets . Diabetologia. 2002. 45(2). 159-173. CrossRef PubMed
  11.  
  12. Dornish M., Kaplan D., Skaugrud 0. Standards and guidelines for biopolimers in tissue-engineered medi¬cal products: ASTM alginate and citosan standard guides . Ann. N. Y. Acad. Sci. 2001. 944. 388-397. CrossRef PubMed
  13.  
  14. Figliuzzi M., Plati T., Cornolti R. et al. Biocompatibility and function of microencapsulated pancreatic islets . Acta Biomaterialia. 2006. 2(2). 221-227. CrossRef PubMed
  15.  
  16. Lee C.H., Wang Y.J., Kuo S.M., Chang S.J. Microen¬capsulation of parathyroid tissue with photosensitive poly(L-lysine) and short chain alginate-co-MPEG . Artif. Organs. 2004. 28(6). 537-542. CrossRef PubMed
  17.  
  18. Lim F., Sun A. M. Microencapsulated islets as bioartificial endocrine pancreas . Science. 1980. 210(4472). 908-910. CrossRef PubMed
  19.  
  20. Picariello L., Benvenuti S., Recenti R. et al. Microencapsulation of human parathyroid cells: an "in vitro" study . J. Surg. Res. 2001. 96(1). 81-89. CrossRef PubMed
  21.  
  22. Schneider S., Feilen P., Cramer H. et al. Beneficial ef¬fects of human serum albumin on stability and func¬tionality of alginate microcapsules fabricated in differ¬ent ways . J. Microencapsul. 2003. 20(5). 627-636. CrossRef PubMed
  23.  
  24. Smidsrad O., Skj?k-Brezk G. Alginate as immobilization matrix for cells . Trends Biotechnol. 1990. 8(3). 71-78. CrossRef  
  25. Testini M., Rosato L., Avenia N. et al. The impact of single parathyroid gland autotransplantation during thyroid surgery on postoperative hypoparathyroidism: a multicenter study . Transplant. Proc. 2007. 39(1). 225-230. CrossRef PubMed
  26.  
  27. Thomusch O., Machens A., Sekulla C. et al. The im¬pact of surgical technique on postoperative hypopara¬thyroidism in bilateral thyroid surgery: a multivariate analysis of 5846 consecutive patients . Surgery. 2003. 133(2). 180-185. CrossRef PubMed
  28.  
  29. Uludag H., De Vos P., Tresco P. A. Technology of mammalian cell encapsulation . Adv. Drug. Deliv. Rev. 2000. 42(1-2). 29-64. CrossRef  
  30. Van Raamsdonk J.M., Chang P.L. Osmotic pressure test: a simple, quantitative method to assess the me¬chanical stability of alginate microcapsules . J. Biomed. Mater. Res. 2001. 54(2). 264-271. CrossRef  
  31. Wang M.S., Childs R.F., Chang P.L. A novel method to enhance the stability of alginate-poly-L-lysine-alginate microcapsules . J. Biomater. Sci. Polymer Edn. 2005. 16(1). 91-113. CrossRef PubMed
  32.  
  33. Winer K. K., Ko C. W., Reynolds J. C. et al. Long-term treatment of hypoparathyroidism: a randomized controlled study comparing parathyroid hormone-(1-34) versus calcitriol and calcium . J. Clin. Endocrinol. Metab. 2003. 88(9). 4214-4220. CrossRef PubMed
  34.  
  35. Zimmermann U., Mimietz S., Zimmermann H. et al. Hydrogel-based non-autologous cell and tissue therapy . Biotechniques. 2000. 29(3). 564-581. PubMed
  36.  
  37. Zimmermann U., Cramer H., Jork A. et al. Microencapsulation-based cell therapy . In.: Biotechnology. Edited by Rehm H.-J. and Reed G. Weinheim: Wiley-VCH, 2001. 547-571. PubMed
  38.  
  39. Zimmermann U., Thtirmer F., Jork A. et al. A novel class of amitogenic alginate microcapsules for long-term immunoisolated transplantation . Ann. N. Y Acad. Sci. 2001. 944. 199-215. CrossRef PubMed

© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2019.