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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2009; 55(2): 50-57


BLOOD CELLS PHAGOCYTIC ACTIVITY AND FREE FATTY ACIDS CONTENT IN RAT BRAIN DURING EXPERIMENTAL DISTURBANCES IN BLOOD SUPPLY

L.M.Yaremenko, T.S. Brjuzgina, A.N. Grabovoy

    Pathology Problems’ Institute of National O.O. Bogomoletz Medical University, Kyiv, Ukraine


Abstract

Phagocytic activity of blood cells and free fatty acids content in rat brain were studied during experimental disturbances of blood supply. It is shown that disturbances of cerebral circulation in rats lead to a depression of a phagocytic part of immunity though during the expressed damage during the early periods its inten­sification is observed. During disturbances in brain circulation, the most significant changes are seeing in the contents of arachidonic and palmitic fatty acids. The level of changes in fatty acids contents and their dynamics depended on the degree of circulatory disturbances. Correlation communications between activity of phagocyte blood cells and changes in fatty acid content in rat brain during circulatory alterations point to the certain dependence on systemic oxidative stress.

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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2021.