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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2009; 55(1): 61-70


O.I. Vorobjova, A.V. Shlyachova, E.V. Veselovskaya

    SI “Institute of Neurology, Psychiatry and Narcology of AMS Ukraine”, Kharkiv, Ukraine


The experimental research of the aggressive behaviour formed under the agonistic conflicts using the model of sensory contacts and «partition» test was studied in intact rats and in rats with cannabis dependence. The comparative analysis of ethological indices enables us to draw a conclusion about the mechanisms of cannabis influence on aggressive behaviour formation and manifestation.

Keywords: aggressive behaviour, cannabis


  1. Augustinovich DF, Alekseenko OV, Bakshta-novskaya IV Dynamic changes in serotonergic and dopaminergic activity of the brain during the development of anxiety depression: an experimental study. Usp. physiol. Science. 2004. 35, N 4. p. 19-40.
  2. Anokhin PK Essays on the physiology of functional systems. M .: Meditsina, 1975. 446 p.
  3. Balashov A.M. Evolution of views on the pathogenesis of cannabinoid dependence. Narcology. 2004. N 11. p.5-12.
  4. Baron R., Richardson D. Aggression. S. Pb .: Piter, 2001. 352 p.
  5. Vedyaev FP, Vorobieva TM Models and mechanisms of emotional stress. K .: Health, 1983. 135 p.
  6. Veselovskaya OV, Shlyakhova AV Features of formation of the subordinate type of behavior of rats at agonistic collisions . Physiol. magazine. 2007. 53, N 2. p. 41-47.
  7. Veselovskaya EV, Shlyakhova AV Changes in rat brain electrogenesis under the influence of cannabinoids. In the book: Materials All-Ukrainian. Science. conf. "Modern issues of physiology and medicine", dedicated. 85th anniversary of the founding of the Department of Human and Animal Physiology and the 100th anniversary of the birth of PE Motsny (September 26-28, 2007) Dnepropetrovsk, 2007. P14.
  8. Vorobieva TM Neurobiology of secondarily acquired motivations . International. honey. magazine. 2002. N 1-2. p. 211-217.
  9. Vorobieva TM, Kolyadko SP., Bevzyuk DA System-neurobiological mechanisms of aggressive behavior . Neurosciences: theoretical and clinical aspects. 2005 1, N 1. P.20.
  10. Kudryavtseva NN, Popova NK Comparative characteristics of the parameters of the aggressive reaction of mice of two genotypes . Journal. higher nervous activities of them. I.P. Pavlova. 1988. In 5. p. 889-895.
  11. Kudryavtseva NN Application of the "partition" test in behavioral and pharmacological experiments . Ros. physiol. magazine. them. I.M. Sechenova. 2002. p. 90-105.
  12. MeningO.Behavior of animals. M.: Mir, 1982. 360p.
  13. Novikov SN Pheromones and mammalian reproduction. L .: Nauka, 1988 211 p.
  14. Poshivalov VP Experimental psychopharmacology of aggressive behavior. L .: Nauka, 1986. 175 p.
  15. Silkis PG Possible mechanism of influence of cannabinoids on signal transmission through basal ganglia . Ros. physiol. magazine. them. I.M. Sechenova. 2002. 88, N 2. p. 144-157. CrossRef
  16. Churyukanov MV, Churyukanov VV Functional organization and therapeutic potential of the endogenous cannabinoid system . Experiment. and clinical pharmacology. 2004. On line.
  17. Yatsenko NM, Tsintsadze T.Sh., Lozova NO Synthetic analogue of cannabinoids WIN 55,212-2 increases the amplitude of glycine activated currents . Physiol. magazine. 2007. 53, N 3. p. 31-37.
  18. Adams L.B., Martin B.R. Cannabis: pharmacology and toxicology in animals and humans . Addiction. 1996. 91,N 11. P. 1585-1614. CrossRef PubMed
  19. Curran H. V., Brignell C, Fletcher C. et al. Cognitive and subjective dose-response effects of acute oral D 9-tetrahydrocannabinol (THC) in infrequent cannabis users . Pharmacology. 2002. 164, N 1. P. 61-70. CrossRef PubMed
  20. Martin B.R., Compton D.R., Little P.J. et al. Pharma­cological evaluation of agonistic and antagonistic ac­tivity of cannabinoids . Structure Activity Relationships Cannabinoids. 1987. P. 108-122. CrossRef
  21. Hales T.G., Lambert J.J. The actions of propofol on in­hibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones . Brit. J. Pharmacol. 1991. 104, N 3. P. 619-628. CrossRef PubMed PubMedCentral

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