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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2009; 55(1): 7-11

A/b-interferon effects on electrophoretic mobility of murine T lymphocytes

E.V. Dolgaya, N.M. Zholobak, N.Ya. Spivak, I.S. Magura

  1. O.O. Bogomoletz Institute of Physiology National Academy of Sciences of Ukraine, Kyiv, Ukraine
  2. D.K. Zabolotny Institute of microbiology and virusologyNational Academy of Sciences of Ukraine, Kyiv, Ukraine


a/b-Interferon (a/b-IFN)-induced early changes in the elec-trophoretic mobility (EPM) of murine splenic T lymphocytes were studied by the microelectrophoresis technique. It has been found that a/b-IFN- treated T lymphocytes have a greater EPM than control cells within first hours of a/b-IFN addition. This change in EPM depends on the concentration of б/в-IFN in the medium and the duration of a/b-IFN interaction with the cells. It is concluded that the a/b-IFN-treated cells have a greater net negative charge of the cell surface than control cells.


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