Integrative function of nervous cells:role of potassium channels
I.S. Magura, E.V. Dolgaya, N.A. Bogdanova.
Ін-т фізіології ім. О.О. Богомольця НАН України, Київ
Abstract
Complex processing and integration of the signals observed in
neurons are facilitated by a diverse range of the gating proper-
ties of the ion channels in this cell type, particularly of the
voltage-gated potassium channels. A distinctive combination
of potassium channels endows neurons with a broad repertoire
of the excitable properties and allows each neuron to respond
in a specific manner to a given input at a given time. The
properties of many potassium channels can be modulated by
second messenger pathways activated by neurotransmitters
and other stimuli. Potassium channels are among the most
frequent targets of the actions of several signaling systems.
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