Українська Русский English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2007; 53(6): 78-84


Effect of cationic and anionicamphiphilic compounds on hypertonic cryohemolysis of mammalian red blood cells

S.S. Ershov, N.A. Pisarenko, N.V. Orlova, N.M. Shpakova.



Abstract

We studied the effect of derivatives of anionic (sodium decyl- and dodecyl- sulphate) and cationic (trifluoperazine, chlorpromazine) amphiphilic compounds on morphological pe- culiarities and hypertonic cryohemolysis of human, rabbit, bo- vine, equine red blood cells. The mentioned substances cause changes in red blood cell shape for all the studied mammals: anionic amphiphils on the discocyte-echinocyte type and cationic ones on discocyte-stomatocyte type. It was revealed a signifi- cant antihemolytic activity of the studied substances under hy- pertonic cryohemolysis of mammalian red blood cells with manifested species differences in the efficiency. The most ef- fective are cationic trifluoperazine and anionic sodium decylsulphate, moreover the latter is much more active for ani- mal red blood cells if compared with human ones.

References

  1. Белоус А.М., Грищенко В.И. Криобиология. – К.: Наук. думка, 1994. – 432 с.
  2. Гордиенко Е. А., Коваленко С. Е. Основные законо- мерности явления гипертонического криогемолиза // Пробл. криобиологии. – 1997. – № 3. – С. 3–7.
  3. Денисова О. Н. Криочувствительность эритроцитов различных видов млекопитающих: Автореф. дис. ... канд. биол. наук. – Харьков, 2006. – 20 с.
  4. Єршов С.С., Орлова Н.В., Шпакова Н.М. Порів- няльний аналіз гіпертонічного кріогемолізу еритро- цитів різних видів тварин при зміні осмотичних і температурних умов середовища // Біологія тварин. – 2006. – 8, №1–2. – С. 123–129.
  5. Кулешова Л.Г Орлова Н.В., Шпакова Н.М. Анти- гемолитическая и трансформирующая активность амфифильных соединений // Пробл. криобиологии. – 2001. – № 1. – С. 9–15.
  6. Начала физиологии / Под.ред.акад. А.Д. Ноздра- ева.– СПб; Лань, 2001. – 1088 с.
  7. Орлова Н.В. Вплив амфіфільних сполук на осмотичну і температурну чутливість еритроцитів: Автореф. дис. ... канд. биол. наук. – Харкiв, 2001. – 17 с.
  8. Шпакова Н. М., Бондаренко В. А. Действие хлорпромазина на температурную и осмотическую чувствительность эритроцитов // Биохимия. – 1991. – 56, № 12. – С. 2125–2130.
  9. 9. Шпакова Н.М., Панталер Е.Р., Бондаренко В.А. Антигемолитический эффект хлорпромазина при гиперосмотическом и холодовом шоке эритроцитов // Там же. – 1995. – 60, № 10. – C. 1624–1631.
  10. 10. Шпакова Н.М., Панталер О.Р. Iнгiбiтори кальмо- дулiну та холодовий шок еритроцитiв Тез.доп. VI Укр. бiохiм. з’їзду. – К., 1992. – Ч.I. – С. 107.
  11. Bereza U., Brewer G., Misukami I. Association of calmodulin inhibition, erythrocyte membrane stabiliza- tion and pharmacological effects of drugs // Biochim. Biophis. Acta. – 1982. – 692, № 2. – P. 305–314.
  12. Bessis M. Red cell shapes. An illustrated classification and its retionale. In: Red Cell Shape; Physiology, Pa- thology, Ultrastructure, Springer-Verlag. – Heidelberg, 1973. – P. 1 –24.
  13. Bogner P., Sipos K., Ludany A. et al. Steady-state vol- umes and metabolism-independent osmotic adaptation in mammalian erythrocytes// Eur. Biophys. J. –2002. – 31, № 2. –P.145 –152
  14. Garnier M., De Preville G., Pilardeau T.P., Boudia D. Relationship between the intra-erythrocyte sodium composition and the membrane lipoprotein composition among different mammal species // Comp. Biochem. Physiol. – 1984. – 77A, № 2. – P. 315–317.
  15. Guerra-Shinohara E.M., Barretto O.C. The erythrocyte cytoskeleton protein 4.2 is not demonstrable in several mammalian species// Braz. J. Med. Biol. Res. – 1999. – 32, № 6. – P. 683–687.
  16. Hagerstrand H., Isomaa B. Amphiphile –induced antihaemolysis is not causally related to shape changes and vesiculation // Chem. – Biol. Inter. – 1991. – 79, № 3. – P. 335–347.
  17. Isomaa B., Hagerstrand H., Paatero G. Shape transfor- mations induced by amphiphiles in erythrocytes // Biochim. Biophys. Acta. – 1987. – 809, № 1. – P. 93–103.
  18. Isomaa B., Hagerstrand H., Paatero G., Engblom A.C. Permeability alterations and antihaemolysis induced by amphiphiles in human erythrocytes // Biochim. Biophys. Acta. – 1986. – 860, № 3 – P. 510–524.
  19. 19. Lim H.W.G., Wortis M., Mukhopadhyay R. Stomato- cyte-discocyte-echinicyte sequence of the human red blood cell: Evidence for the bilayer-couple hypothesis from membrane mechanics // Proc. Natl. Acad. Sci. USA. – 2002. – 99, № 26. – P. 16766–16769.
  20. 20. Sheetz M.P., Singer S.J. Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte in- teractions// Ibid. – 1974. – 71, № 11. – P. 4457–4461.
  21. Simons K., Vaz W.L. Model systems, lipid rafts, and cell membranes //Annu. Rev. Biophys. Biomol. Struct. – 2004. – 33. – P. 269–295.
  22. Takahashi T., Noji S., Erbe E.F. et al. Cold shock hemolysis in human erythrocytes studied by spin probe method and freeze-fracture electron microscopy// Biophys. J. – 1986. – 49, №.2. – P. 403–410.
  23. Takahashi T., Williams R. J. Thermal shock hemolysis in human red cells. I. The effects of temperature, time, and osmotic stress // Cryobiology. – 1983. – 20, № 5. – P. 507–520.
  24. Virtanen J. A., Cheng K. H., Somerharju P. Phospho- lipid composition of the mammalian red cell membrane can be rationalized by a superlattice model// Proc. Natl. Acad. Sci. USA. –1998. – 95, №. 9. – P. 4964–4969.
  25. Wessels J.M., Veerkamp J.H. Some aspects of the os- motic lysis of erythrocytes III. Comparison of glycerol permeability and lipid composition of red blood cell membranes from eight mammalian species // Biochim. Biophys. Acta. –1973. – 291, № 1. – P. 190–196.

© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2019.