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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2007; 53(2): 70-77

Role of cell adhesion molecules inthe modulation of synaptic activity

A.G. Nikonenko, G.G. Skibo

    O.O.Bogomoletz Institute of Physiology NAS of Ukraine,Kyiv



Cell adhesion molecules (CAMs) can influence various devel- opmental events, including cell migration, proliferation, and differentiation. Recent advances have provided evidence that in addition to their adhesive properties, CAMs can affect intracellular signalling and synaptic function. This review fo- cuses on the role of CAMs in the modulation of synaptic activity. Some mechanisms are being discussed including one that involve the ability of CAMs to initiate the formation of scaffolds permitting efficient signalling

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