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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2000; 46(5): 71-76


Influence of the Biopreparation Likvorin by the IntraventricularyInfusing on General Convulsive Activity of Rats

Tkach V. V.

    Crimea State University, Simferopol


Abstract

It was studiet anticonvulsive action of the biopreparation licvorin had been made from a cerebrospinal fluid (CSF) of a cattle on the epiliptic activity provoking by korasol. The preparation was infused intraventriculary. Research showed preparation had the antiepileptic effect. It was manifested by decreasing expressiveness of convulsions, averting of general epileptic fit and mortality. Anticonvulsive action of the biopreparation licvorin was registrated in 2 hours and was achieved maximum effect 24 hours after injection. Anticonvulsive properties of the biopreparation licvorin realized by influence his active factors on structures of a brain, specifically on the GABAdependent systems.

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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2018.