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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2006; 52(4): 40-46

Influence of carbahol and atropine on the motor cortex neurons in cat duringoperant reflex

E.A. Schyglo

    O.O. Bogomoletz Institute of Physiology National Academyof Sciences of Ukraine, Kyiv



Abstract

Effects of carbachol and atropine on the caused and back- ground impulse neurons activity during operant reflex were studied on twenty motor cortex neurons. Motor cortex neurons in dependence of changes impulse neurons activity after carbachol administration have been divided into two groups; the first group includes neurons with a long influence on im- pulse activity and the second – with short. Carbachol applied by ionophoresis to motor cortex promoted authentic increase of background impulse activity and duration of the caused reaction in both groups. Abministration of atropine, an an- tagonist of m-cholinergic receptors significantly reduced pa- rameters of background impulse activity and duration of the caused reaction. It was suggested that acetylcholine released by terminals of the cholinergic fibers in natural conditions takes part in maintenance of motor cortex neuron background activity and provides sufficient intensity of the motor commands generated by these cells; the given effects mediated by m-cholinergic receptors

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