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Influence of carbahol and atropine on the motor cortex neurons in cat duringoperant reflex
E.A. Schyglo
O.O. Bogomoletz Institute of Physiology National Academyof Sciences of Ukraine, Kyiv
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Abstract
Effects of carbachol and atropine on the caused and back-
ground impulse neurons activity during operant reflex were
studied on twenty motor cortex neurons. Motor cortex neurons
in dependence of changes impulse neurons activity after
carbachol administration have been divided into two groups;
the first group includes neurons with a long influence on im-
pulse activity and the second – with short. Carbachol applied
by ionophoresis to motor cortex promoted authentic increase
of background impulse activity and duration of the caused
reaction in both groups. Abministration of atropine, an an-
tagonist of m-cholinergic receptors significantly reduced pa-
rameters of background impulse activity and duration of the
caused reaction. It was suggested that acetylcholine released
by terminals of the cholinergic fibers in natural conditions
takes part in maintenance of motor cortex neuron background
activity and provides sufficient intensity of the motor
commands generated by these cells; the given effects mediated
by m-cholinergic receptors
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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.
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