Українська Русский English

ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2005; 51(6): 49-57


Assessment of the cerebrovascularreserve in humans

A.N. Volyansky.

    Main Military Clinical Hospital, Kyiv, Ukraine


Abstract

A new approach of assessment of cerebrovascular reserve in healthy human is proposed. Twenty-two healthy men volun- teers aged 25-43 were examined. Investigation of cerebral blood circulation in each of them was implemented for the six times with one-week interval. The cerebral blood flow was measured by use of Doppler ultrasound. Blood flow velocity in the middle cerebral artery and homolateral internal jugular vein and pulsative index in this artery were considered as basic structural elements of cerebral blood circulation in this work. Breath-holding, hyperventilation and stress tests served as functional tests. It was shown that degree of basic parameters synchronization in a system cerebral blood circulation under the influence of functional load determine his cerebrovascular reserve. This method of cerebrovascular reserve estimation could be used for determination of psychophysical readiness of separate human to professional occupation.

References

  1. Буров А.Ю., Герасимов А.В., Четверня Ю.В.Автоматизированный профессиональлный отбор иконтроль профессиональной работоспособностиоператоров энергопредприятий на базе ПЭВМIВМ. – В кн.: Энергетика и электрификация. – К.:Технiка, 1992. – №2. – С.29–32.
  2. Дорошев В.Г. Системный подход к здоровьюлетного состава в ХХІ веке. – М.: Паритет Граф,2000. – 368 с.
  3. Клиническое руководство по ультразвуковойдиагностике / Под ред. В.В.Митькова. – М.: ВИДАР,1997. – 387 с.
  4. Куликов В.П., Гречишников В.Н., Сидор М.В.Реакция мозговой гемодинамики на сочетанныестрессорные воздействия // Патол. физиология иэксперим. терапия. – 2005. – №1. – С. 7–9.
  5. Москаленко Ю.Е., Бекетов А.И., Орлов Р.С.Мозговое кровообращение: Физико-химическиеприемы изучения. – Л.: Наука, 1988. – 160 с.
  6. Мчедлишвили Г.И. Микроциркуляция крови:Общие закономерности регулирования и нару-шений. – Л.: Наука, 1989. – 296 с.
  7. Aaslid R., Newell D.W., Stoss R. et al. Assessment ofcerebral autoregulation dynamics from simultaneousarterial and venous transcranial Doppler recordings inhumans // Stroke. – 1991. – 22, №6 – P. 1148–1154.
  8. Alvares Perez F.J, Segura Martin T., Serena Leal J. etal. The normal values of the haemodinamic reserve (HR)evaluated by the CO2 test // Neurologia. – 2002. – 17,№5 – P. 231–237.
  9. 9. Doepp F., Schreiber S.J, Brunecker P. et al. Ultrasonog-raphic assessment of global blood volume in healthyadults // J.Cereb.Blood Flow Metab. – 2003. – 23, №8 –P. 972–979.
  10. 10. Kevin M., BarretB.A., Robert H. et al. Basilar andcerebral arterial artery reserve: a comparative studyusing transcranial Doppler and breath-holding tech-niques // Stroke. – 2001. – 32, №12 – P. 2793–2799.
  11. Marcus H.S., Harrison M.J. Estimation of cerebrovas-cular reactivity using transcranial doppler, includingthe use of breath-holding as the vasodilatatory stimu-lus // Ibid. – 1992. – 23, №3 – P. 668–673.
  12. Muller H.R. Ultrasonic imaging of the internal jugularvein // J.Neuroimaging. – 1991. – 1, №2 – P. 74–82.
  13. Norcliff L.J., Rivera C.M., Claydon V.E. et al.Cerebrovasculal responses to hypoxia and hypocap-nia in high-altitue dwellers // J.Physiol. – 2005. – 566,№1 – P. 287–294.
  14. Ratnatunga C., Adiseshiah M. Increase in middle cere-bral artery velocity on breath holding: a simplified testof cerebral perfusion reserve // Eur.J.Vasc.Surg. – 1990. –4, №5 – P. 519–536.
  15. Schreiber S.J., Lurtzing F., Gotze R. et al. Extrajugularpathways of human cerebral venous blood drainageassessed by duplex ultrasound // J.Appl.Physiol. –2003. – 94, №5 – P. 1802–1807.
  16. Stoll M., Hammann G.F. Cerebrovascular reservecapacity // Nervenarzt. – 2002. – 73, №8. – P.711–719.
  17. Valdueza J.M., Draganski B, Hoffman O. et al. Analysisof CO2 vasomotor reactivity and vessel diameterchanges by simultaneous venous and arterial Dopplerrecordings // Stroke. – 1999. – 30, №1 – P. 81–87.
  18. Wong E.K., Bull W.D., Boulay F.H. et al. Regionalcerebral blood flow and oxygen consumption in humanaging // Neurology. – 1973 – 23, №6. – P.949–952.

© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2018.