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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2005; 51(6): 30-36


Effects of bradykinin and capsaicininjections into feline m. gastrocne-mius-soleus on stretch-evokedpostsynaptic responsein homosynaptic motoneurones

L.A. Bugaychenko, A.I. Pilyavskii, A.I. Kostyukov.

    O.O.Bogomoletz Institute of Physiology, NAS of Ukraine,Kyiv


Abstract

Responses of gastrocnemius-soleus motoneurones to stretches of the homonymous muscles were recorded intracellularly in 63ISSN 0201-8489 the decerebrated cats during intramuscular injections (IMI) of bradykinin or capsaicin into the muscles. Effects of IMI on EPSPs and spikes evoked by stretches of the G-S muscles were studied in 6 motoneurones. Stretch-evoked EPSPs and firing were predominantly suppressed after IMIs, with the exception of slight increase of EPSPs up to 150 s after brady- kinin injection, followed by theirs distinct decrease. The sup- pression of spike activity was followed by restoration within 500–800 s after bradykinin injection. Stretch-evoked EPSPs and firing were depressed after capsaicin injection; control level of motoneurones activity was seemed to be unrecoverable for quite a long time. No background IPSPs were observed after algesic injections and presynaptic inhibition was considered as plausible reason for the observed suppression of motoneurones activity.

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