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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2004; 50(4): 123-127


Induced contractile activity of smooth musclesof the colon in rats after no-syntase inhibition

O.G. Shadrin, S.M. Gotsulyak, A.G. Tsypkun

    Institute of Pediatrics, Obstetrics and Gynecology Academyof Medical Sciences of Ukraine, Kiev.


Abstract

NO involvment in the mechanisms of the contractile activity of the smooth muscle cells was studied in the colon. The differences in the effects of different transmitters on the kinetics of the contractile activity after NOS inhibition have been determined.

References

  1. Реутов В.П., Сорокина Е.Г., Охотин В.Е. и соавт. Циклические превращения оксида азота в организме млекопитающих. –М.: Наука, 1998. – 156 с.
  2. Физиология и патофизиология желудочно-кишеч- ного тракта. Под ред. Дж.М.Полак (пер. с англ.) М.: Медицина, 1989. – 496 с.
  3. De Ponti F., Tonini M. Irritable bowel syndrome. New agents targeting serotonine receptor subtypes // Drugs. – 2001. – 61, №3. – P. 317-32.
  4. Gustafsson L.E., Wiklund N.P., Wiklund S.U.,Ceder- qvist B., Persson M.G. and Moncada S. Modulation of autonomic neuroeffector transmission by nitric ox- ide-like activity in guinea pig smooth muscle. In: Ni- tric Oxide from L-arginine: A Bioregulatory System, ed. By Moncada S & Higgs E.A., Elsevier, Amsterdam. –1990. – P. 177-181.
  5. Jones R, Lydeard S. Irritable bowel syndrome in the general population // BMJ. – 1992. – 304. – P. 87-90.
  6. Lundberg J.O., Lundberg J.M., Alving K., Weitzberg E. Nitric oxide and inflamation:The answer is blowing in the wind // Nature Medicine. – 1997. – 3. – P. 30-31.
  7. Mizuta Y., Takahashi T., Owyang C. Nitrergic regulation of colonic trasit in rats // Amer. J. Physiol.– 1999.– 227.– P. G275-G274.
  8. Takahashi T., Owyang C. Regional differences in the nitrergic innervation between the proximal and the dis- tal colon in rats // Gastroenterology.- 1998.– 115.– P. 1504-1512.
  9. 9. ThompsonW.G., Irvine E.J., Pare P., Ferrazzi S., Rance L. Functional gastrointestinal disorders in Canada: first population-based survey using Rome II criteria with suggestions for improving the questionnaire // Dig. Dis. Sci. – 2002. – 47, №1. – P. 225-235.
  10. 10. Thomson S, et al. Symptoms of irritable bowel in school children: prevalence and psychosocial effects // J. Pediatr. Health. Care. – 1996. – 10, №6. – P. 280-285.

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