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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2003; 49(3): 139-143

Mathemaтical methods for invesтi-gaтing тне reliabiliтy of organisms functioning under тне extreme condiтions of нigh mountains

P.V.Beloshitsky, Yu.N.Onopchuk, D.I.Marchenko, N.I.Aralova

    International Centre for Astronomical, Medical andEcological Research NASU, RAS and government ofKBR,


The health of а person and his capacity for work under conditions of high mountains in тапу respects is deter mined bу the reliability of the function of physio logical systems. Mathematical methods of both the reliability theory and mathematical simulation of basic functional systems are proposed to bе used for investigating the reliability. It is shown that the most suitable reliability model for living systems is а chain model-a successive connection of links representing separate functional systems of organism. Besides, the weakest links determining the reliability of functioning of the whole organism under the extreme conditions of high mountains even for а healthy person are-respiration, blood circulation, thermoregulation and psychophysiological systems. Quantitative characteristics of the reliability of these systems are determined through the main indicators. The influence of non-sufficient contents of охуgen in respiration mixture, low atmospheric pressure, low temperatures of the environment are simulated by computer models of organism. An analyses of modeling data shows that moderate physical loading improves indicators of organisms adaptivety to external conditions of high mountains and promotes the increasing of persons саpacity for work and the reliability of his functioning.


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© National Academy of Sciences of Ukraine, Bogomoletz Institute of Physiology, 2014-2024.