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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2003; 49(3): 63-69


Peculiarities of the reaction of respiration tohypoxia in aging

O.V.Korkushko, V.Yu.Lishnevskaya, V.P.Chizhova, T.V.Ruhlyada, G.V.Duzhak

    Institute of gerontology AMS of Ukraine, Kie


Abstract

The purpose of the research was to investigate the peculiarities of ventilatory reaction to hypoxia with the elderly and old people. 27 practically healthy young (20-35 years), 24 elderly (60-74 years) and old (older 74 years) people were examined. The influence of hypoxia on the gas exchange was investigated during the respiration of gas mixtures with 17 % and 12,5 % of oxygen content (during 12 minutes), that corresponds to 1500 m and 4000 m above sea level. The parameters of ventilating function of the lung were determined on the spirograf СГ-1М. Oxygen tension in arterial blood (paO2) was determined with the device «AVL» by «OMNI» (Austria). The curves of ventilating dependence on paO2 for the young and old people are plotted using the mathematical model. It was shown, that with aging the “steepness” of curve’s dependence on the ventilatory answer from the degree of hypoxemia decreases, that testifies to the decrease of chemoreflex sensitivity.

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