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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2002; 48(4): 39-42


Effects of ethanol on endothelium of pulmonary artery

S.M. Marchenko

    А.А.Bogomoletz Institute of PhysiologyNational Academy of Sciences of Ukraine, Kiev



Abstract

Effects of ethanol on membrane potential and intracellular calcium concentration in intact endothelium of isolated pulmonary arteries were investigated. Ethanol evoked hyperpolarization and biphasic increase in [Ca2+]i in the endothelium due to both Ca2+ release from intracellular stores and Ca2+ entry from extracellular solution. These data allow endo- thelium- dependent dilation of pulmonary artery evoked by ethanol to be explained.

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