In order to develop new approaches to the psychophysiological selection of operators, 219 male servicemen aged 20 to 40 years old with experience in operating unmanned aerial systems of the first class Light and involved in a wide range of professional tasks were examined. To study their psychophysiological status, modified methods were used using the PFI-2 hardware and software complex. The following indicators were determined: accuracy of reaction to a moving object, strength of nervous processes, functional mobility of nervous processes, simple visual-motor reaction, complex visual-motor reaction, orientation in space, and visual memory. To identify a set of informative indicators that can best divide the analyzed group of operators into 3 clusters, a stepwise discriminant analysis was applied. The technique was developed to obtain several psychophysiological profiles of vocational aptitude, equally effective in terms of content. The statistical discrepancy of these profiles has been established. Ways of evaluating the superiority of these profiles have been shown. The principle of “necessary diversity” in the implementation of occupational psychophysiological selection of operators working in conditions with increased danger has been proposed and discussed. A number of advantages of using this principle to increase accuracy and expand the contingent of persons subject to occupational psychophysiological selection have been identified. The technology of graphical presentation of psychophysiological profiles of operators of unmanned aerial complexes was developed for the purpose of assessment of suitability for professional tasks.