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INFLUENCE OF SEROTONIN ON THE METABOLISM OF BONE TISSUE
I.G. Litovka
Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine, Ukraine
DOI: https://doi.org/10.15407/fz68.05.079
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Abstract
This literature review presents data on the influence of
serotonin on the metabolism of bone tissue. The mechanisms
by which serotonin affects the formation and resorption of
bone, depending on the site of synthesis (central or peripheral),
as well as the cells and receptor subtypes that are activated,
have been considered. A number of issues for further research
are highlighted, in particular, the dose-response relationship
and side effects during chronic and long-term treatment with
various selective serotonin reuptake inhibitors.
Keywords:
serotonin; metabolism; bone tissue
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