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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2022; 68(5): 79-88


I.G. Litovka

    Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine, Ukraine


This literature review presents data on the influence of serotonin on the metabolism of bone tissue. The mechanisms by which serotonin affects the formation and resorption of bone, depending on the site of synthesis (central or peripheral), as well as the cells and receptor subtypes that are activated, have been considered. A number of issues for further research are highlighted, in particular, the dose-response relationship and side effects during chronic and long-term treatment with various selective serotonin reuptake inhibitors.

Keywords: serotonin; metabolism; bone tissue


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