REALIZATION OF ANXIETY AND AGGRESSION IN RATS WITH ALCOHOL DEPENDENCE IN THE CONDITIONS OF ZOOSOCIAL CONFLICT
O.V. Veselovska, A.V. Shliakhova, N.O. Levicheva, D.O. Bevzyuk, O.G. Berchenko, O.O. Prikhodko
SI “Institute of Neurology, Psychiatry and Narcology of National Academy of Medical Sciences of Ukraine”, Kharkiv, Ukraine
DOI: https://doi.org/10.15407/fz68.04.066
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Abstract
The aim of the work was to study the features of the
relationship between anxiety and aggressiveness in rats with
alcohol dependence when modeling a long-term zoo conflict situation. Neuroethological studies were carried out using a
multi-parameter method for assessing anxiety. Aggressiveness
and submissiveness were studied when creating agonistic
collisions as a result of conflict social interactions and psychoemotional stress in a confined space using the sensory contact
technique and the “partition” test. Alcohol dependence in
rats was caused by voluntary intake of alcoholized food.
The experimental group consisted of rats subjected to
alcoholization and agonistic collisions. The comparison group
included rats with agonistic collisions. Alcoholization of rats
increased the baseline low level of anxiety. Confrontational
relationships caused in 54% of alcoholized rats a consistently
high level of impulsive aggression together with the desired
aggression and a decrease in anxiety. At the same time, 46%
of rats exhibited submissive behavior. In animals that had
a baseline low level of anxiety and were not subjected to
alcoholization, manifestations of aggression were noted only
in 30% of rats and they had a fading character in the dynamics
of zoo conflict relations. Animals with a baseline high level of
anxiety exhibited submissive behavior under these conditions.
Thus, the role of a basic low level of anxiety in the formation
of emotional disorders was shown: an increase in the level of
anxiety in alcoholism and the dominance of impulsive and
desired aggression in conditions of zoosocial conflict.
Keywords:
the basic level of anxiety; aggression; submissiveness; zoosocial conflict; alcohol dependence.
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