The purpose of the work is to assess the levels of IgG, IgM and neutralizing antibodies to SARS-CoV-2 in medical workers during the year (2020-2021) before the start of mass vaccination, depending on the presence of clinical symptoms and positive PCR test. It is established that people without antibodies to SARSCoV-2 do not have neutralizing antibodies. The antibody levels, as well as percentage of neutralization, were higher in individuals who had just recovered from Covid-19 and have positive PCR at the beginning of the disease compared to those who had no clinical manifestation. There was a positive correlation between the level of IgG and percentage of neutralization. In persons without pronounced clinical symptoms of coronavirus infection, moderately positive neutralizing antibodies prevail, whereas in the vast majority of recovered individuals they are highly positive.