EXTRACELLULAR PROTEASOMES
I. Prudnikov1, V. Tsyvkin1, A. Smirnov1, I. Pristash1, M. Syrko2
- Bogomoletz Institute of Physiology of NAS of Ukraine, Kyiv, Ukraine
- Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz66.05.073
Abstract
Little-known to a wide range of specialists details of the
functioning of one of the main participants in cellular
metabolism – a complex of neutral proteases with their
regulators, which is called “proteasome” – are observed in this
paper. The review analyzes the works of recent years devoted
to the study of the participation of proteasomes in intercellular
signaling and catabolism of regulatory and signaling proteins
in the extracellular space.
Keywords:
exosome; protease; proteasome; signalization.
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