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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2019; 65(2): 43-51

CHANGES IN BRAIN ELECTRICAL ACTIVITY DURING THE REHABILITATION OF SERVICEMEN WITH REMOTE CONSEQUENCES OF COMBAT MENTAL TRAUMA

V.V. Kalnysh1,2, A.V. Shvets2, S.S. Pavlyuk2

  1. SI “Kundiev Institute of occupational health of National Academy of Medical Sciences of Ukraine”, Kyiv, Ukraine
  2. Ukrainian Military Medical Academy, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz65.02.043


Abstract

The neurophysiological features of bioelectric activity restoration of the brain in 32 soldiers aged 32 ± 5.6 years during their psychomedical rehabilitation due to posttraumatic stress disorder (PTSD) as a result of the influence long-term and intense stressful combat conditions have been studied. The computer electroencephalography (EEG) method using the “DX-system” encephalograph and the NeuroResearcher® Innovation module was used to evaluate bioelectric activity of the brain. To process the results, methods of descriptive statistics and correlation analysis have been used. The coefficients of asymmetry and multicollinearity were calculated. The obtained data testify to improvement of EEG profiles after rehabilitation of persons with PTSD. There has been found an increase in the correlation of characteristics in the α, β1, θ rhythms at the frontal area of the brain on the background of a general decrease in the number of reliable correlations after the rehabilitation of individuals with PTSD, which may indicate more synchronous activity of the brain at the frontal area and normalization (decrease) of the spectral frequency peak in β1 activity after rehabilitation. It was shown that the correlation of electrical activity in dual points of the brain in the frontal zone is reliable (p <0.01) with closed eyes in α-range before and after rehabilitation, and it disappears under mental load in the α- and β1-ranges after rehabilitation. Significant positive changes (more than 1.5 times) in correlation data of multicollinearity indicators in the frontal area with closed eyes in β2 and θ bands have been revealed. The stage diagnostics procedure and application of the indicator of integral connectivity of EEG components of military personnel with PTSD during their psychomedical rehabilitation have been proposed.

Keywords: electroencephalography; post-traumatic stress disorder; adjustment disorders; combat operation participants; psychomedical rehabilitation.

Full text: (PDF, in Ukrainian)

References

  1. Duan H, Wang L, Wu J. Psychophysiological correlates between emotional response inhibition and posttraumatic stress symptom clusters. Sci Rep. 2018; 8(1): 16876. doi:10.1038/s41598-018-35123-x. CrossRef PubMed PubMedCentral
    2.  
  2. Sheerin CM, Franke LM, Aggen SH, Amstadter AB, Walker WC. Evaluating the Contribution of EEG Power Profiles to Characterize and Discriminate Posttraumatic Stress Symptom Factors in a Combat-Exposed Population. Clin EEG Neurosci. 2018; 49 (6) : 379-387. doi:10.1177/1550059418767583. CrossRef PubMed
    3.  
  3. Kondratieva OG. Kondratieva AA. Nabiyev RG. Strokin AA. The study of the characteristics of bioelectrical activity of the brain in the formation of post-traumatic stress disorder among the employees of the Ministry of Internal Affairs. Basic Res. 2014; 12 (part 2): 317-321. [Russian].
    4.  
  4. Bekhtereva NP. Healthy and diseased human brain. L.: Science, 1980; 261. [Russian].
    5.  
  5. Robinson BL, Shergill SS. Imaging in posttraumatic stress disorder. Curr Opin Psychiatry. 2011; 24(1): 29-33. CrossRef PubMed
    6.  
  6. Lobo I, Portugal LC, Figueira I, Volchan E, David I, Garcia Pereira M, de Oliveira L. EEG correlates of the severity of posttraumatic stress symptoms: A systematic review of the dimensional PTSD literature. J Affect Disord. 2015; 1 (183): 210-220. doi: 10.1016/j.jad.2015.05.015. CrossRef PubMed
    7.  
  7. Meyer T, Smeets T, Giesbrecht T, Quaedflieg CW, Smulders FT, Meijer EH, Merckelbach HL. The role of frontal EEG asymmetry in post-traumatic stress disorder. Biol Psychol. 2015; 108: 62-77. doi: 10.1016/j.biopsycho.2015.03.018. CrossRef PubMed
    8.  
  8. Rigoli MM, Silva GR, Oliviera FR, et al. The role of memory in posttraumatic stress disorder: implications for clinical practice. Trends Psychiatry Psychother. 2016; 38(3):119-27. CrossRef PubMed
    9.  
  9. Agren T. Human reconsolidation: A reactivation and update. Brain Res Bul. 2014; 105:70-82. CrossRef PubMed
    10.  
  10. Fernandez R, Bavassi L, Forcato C, et al. The dynamic nature of the reconsolidation process and its boundary conditions: Evidence based of human tests. Neubiol Learning and Memory. 2016; 130:202-12. CrossRef PubMed
    11.  
  11. Dunbar AB, Taylor JR. Reconsolidation and psychopathology: Moving towards reconsolidation-based treatments. Neurobiol Learn Mem. 2017; 142:162-71. CrossRef PubMed PubMedCentral
    12.  
  12. Shadrina IV., Dedova KN., Pugachev AN. Neurophysiological features of the brain (according to the results of the analysis of EEG indicators) and their influence on the psychological characteristics of patients with post-traumatic stress disorder. Bull SUSU. 2011; 7: 84-6. [Russian].
    13.  
  13. Förster E., Ryants Yu. Methods of correlation and regression analysis. M: Finance and Statistics, 1983; 302. [Russian].
    14.  
  14. Meyer T, Smeets T, Giesbrecht T, et al. The role of frontal EEG asymmetry in posttraumatic stress disorder. Biol Psychol. 2015; 108:62-77. CrossRef PubMed
    15.  
  15. Begic D, Hotujac L, Jokic-Begic N. Electroencephalographic comparison of veterans with combat-related post-traumatic stress disorder and healthy subjects. Int J Psychophysiol. 2001; 40(2):167-72. CrossRef  
  16. Badura-Brack AS, Heinrichs-Graham E, McDermott TJ, et al. Resting-state neurophysiological abnormalities in posttraumatic stress disorder: a magnetoencephalography study. Front Hum Neurosci. 2017; 11: 197-205. CrossRef PubMed PubMedCentral
    17.  
  17. Jokic-Begic N, Begic D. Quantitative electroencephalogram (qEEG) in combat veterans with post-traumatic stress disorder (PTSD). Nord J Psychiatry. 2003; 57(5):351-7. CrossRef PubMed
    18.  
  18. Imperatori C, Farina B, Quintiliani MI, et al. Aberrant EEG functional connectivity and EEG power spectra in resting state post-traumatic stress disorder: as LORETA study. Biol Psychol. 2014; 102:10-7. CrossRef PubMed
    19.  
  19. Huang MX, Yurgil KA, Robb A. Voxel-wise resting-state MEG source magnitude imaging study reveals neurocircuitry abnormality in active duty service members and veterans with PTSD. Neuroimage Clin. 2014; 5:408-19. CrossRef PubMed PubMedCentral
    20.  
  20. McKenzie S, Eichenbaum H. Consolidation and reconsolidation: two lives of memories? Neuron. 2011; 71 (2): 224-33. CrossRef PubMed PubMedCentral
    21.  
  21. Carega MB, Girardi CE, Suchecki D. Understanding posttraumatic stress disorder through fear conditioning, extinction and reconsolidation. Neurosci Biobehav Rev. 2016; 71: 48-57. CrossRef PubMed
    22.  

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