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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)
DOI: https://doi.org/10.15407/fz

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2019; 65(1): 20-25


BEHAVIORAL CONSEQUENCES OF ENTEROBIASIS IN RATS

A.V. Savotchenko, M.O. Semenikhina, I.V. Krasnianchuk, R.I. Bogovyk, A.E. Honcharova, E.V. Isaeva

    O.O. Bogomoletz Institute of Physiology of the National Agademy of Sciences of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/fz65.01.020

Abstract

Representatives of the family Oxyuridae are the most common parasites of laboratory rodents. The aim of the present study was to clarify the behavioral consequences of enterobiasis in laboratory rats. Enterobiasis was induced by infecting of adult Wistar rats with eggs of Syphacia muris and Aspiculuris tetraptera. The level of anxiety and emotionality, sociability and general social interaction, as well as the fear associative memory formation were evaluated in rats with and without pinworm invasion. The significant increase in the anxiety level was observed in rats with enterobiasis. We did not find any changes in other behavioral measures in our studies. The analysis of the leukocyte formula showed a tendency to increase the number of eosinophils in the blood of infected rats, which may indicate an implementation of the immune response due to enterobiasis.

Keywords: affective behavior; enterobiasis; behavioral tests; immune response

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