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ISSN 2522-9028 (Print)
ISSN 2522-9036 (Online)

Fiziologichnyi Zhurnal

is a scientific journal issued by the

Bogomoletz Institute of Physiology
National Academy of Sciences of Ukraine

Editor-in-chief: V.F. Sagach

The journal was founded in 1955 as
1955 – 1977 "Fiziolohichnyi zhurnal" (ISSN 0015 – 3311)
1978 – 1993 "Fiziologicheskii zhurnal" (ISSN 0201 – 8489)
1994 – 2016 "Fiziolohichnyi zhurnal" (ISSN 0201 – 8489)
2017 – "Fiziolohichnyi zhurnal" (ISSN 2522-9028)

Fiziol. Zh. 2018; 64(1): 52-58


K.V. Yatsenko

  1. Bogomoletz Institute of Physiology of NAS of Ukraine, Kyiv, Ukraine
  2. “Neurological clinic of doctor Yatsenko”, Kyiv, Ukraine


The effect of combined treatment with transcranial direct current stimulation (tDCS) on cerebral blood flow in patients with symptomatic epilepsy was studied. 29 patients with symptomatic epilepsy were examined and received the course of treatment. The comparison group was formed from 14 children who received the course of basic medical and rehabilitation procedures. The main group included 15 children who, in addition to the same therapy, received a course of tDCS. A transcranial Doppler ultrasound examination of head blood vessels was used for the study of cerebral hemodynamics in children with symptomatic epilepsy before and after combined treatment with tDCS. After the course of tDCS, the children had a marked improvement in the EEG pattern, and also tDCS significantly reduced the high mean blood flow velocity per cycle (MFV) in the basilar artery (BA), MCA and ACA (20.5, 17.2 and 7.9%, respectively); in the comparison group no statistically significant positive dynamics was observed. tDCS significantly increased the low MVF in the BA, MCA and ACA (25.1, 20.9 and 10.2%, respectively); a statistically significant increase of MVF by 12.7% was only in the CMA in the comparison group of patients. Our data indicate that the use of tDCS in the combined treatment of patients with epilepsy improves cerebral hemodynamics in 84% of patients, in contrast to 528% in the comparison group. Including the method of tDCS to the complex treatment of patients with epilepsy improves the effectiveness of treatment and may also positively influence the clinical course of the disease.

Keywords: Transcranial Doppler, Epilepsy, Transcranial Direct Current Stimulation.


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